About The Study: This nationwide case-time-control study revealed an increased risk of miscarriage associated with benzodiazepine use during pregnancy after accounting for measurable confounders, and results were unlikely to be due to unmeasured confounding. These findings underscore the necessity for health care professionals to meticulously balance the risk-benefit ratio when considering the use of benzodiazepines to treat psychiatric and sleep disorders during pregnancy.
Authors: Fei-Yuan Hsiao, Ph.D., of National Taiwan University in Taipei, Taiwan, is the corresponding author.
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(10.1001/jamapsychiatry.2023.4912)
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Journal
JAMA Psychiatry