News Release

Antibiotic prophylaxis and infective endocarditis incidence following invasive dental procedures

JAMA Cardiology

Peer-Reviewed Publication

JAMA Network

About The Study: This systematic review and meta-analysis including data on 1.1 million cases of infective endocarditis found that antibiotic prophylaxis was associated with a reduced risk of infective endocarditis following invasive dental procedures in individuals at high risk but not in those at moderate or low/unknown risk. Currently, there is insufficient data to support any benefit of antibiotic prophylaxis in individuals at moderate risk. 

Authors: Federica Turati, Ph.D., of the Università degli Studi di Milano in Milan, Italy, and Katherine France, D.M.D., M.B.E., of the University of Pennsylvania in Philadelphia, are the corresponding authors.

To access the embargoed study: Visit our For The Media website at this link 


Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.

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Media advisory: This study is being released to coincide with presentation at the American College of Cardiology’s Annual Scientific Session. 

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