News Release

Cancer stage compared with mortality as end points in randomized clinical trials of cancer screening


Peer-Reviewed Publication

JAMA Network

About The Study: In this systematic review and meta-analysis that included 41 randomized clinical trials of cancer screening, incidence of late-stage cancer may be a suitable alternative end point to cancer-specific mortality for some cancer types, but is not suitable for others. These results have implications for clinical trials of multicancer screening tests. 

Authors: Hilary A. Robbins, Ph.D., M.H.S., M.S.P.H., of the International Agency for Research on Cancer in Lyon, France, is the corresponding author.

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Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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Media advisory: This study is being released to coincide with presentation at the American Association for Cancer Research Annual Meeting 2024.

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