Article Highlight | 2-Jun-2024

External ventricular drainage timing in traumatic brain injury

Mary Ann Liebert, Inc./Genetic Engineering News

A new study in the peer-reviewed Journal of Neurotrauma shows that in patients with moderate to severe traumatic brain injury (TBI) that need an external ventricular drain (EVD) insertion to control intracranial hypertension, early (<24-hours post-injury) insertion may result in better long-term functional outcomes. Click here to read the article now.

The investigators compared 6-month neurological outcomes between patients with moderate to severe TBI who received early EVD insertion versus later (more than 24-hours after injury) EVD insertion. The results showed that late EVD insertion was associated with an increased risk of death or severe disability at 6-months follow-up.

“Our study findings support the hypothesis that earlier EVD insertion may lead to improved functional neurological outcomes following m-sTBI and imply that earlier use of an EVD (within 24-hours) is likely to be more effective in the management of m-sTBI, as opposed to a later ‘rescue’ intervention,” stated the investigators.

“Using pooled data from several different studies, these researchers found that early insertion of external ventricular drains in patients with moderate or severe traumatic brain injury was associated with better six-month outcomes than late insertion. These exciting results open up new directions for future research and may already impact current management of these patients,” says Alex Valadka, MD, Deputy Editor of Journal of Neurotrauma, from the University of Texas Southwestern Medical Center.

About the Journal

Journal of Neurotrauma is an authoritative peer-reviewed journal published 24 times per year in print and online that focuses on the latest advances in the clinical and laboratory investigation of traumatic brain and spinal cord injury. Emphasis is on the basic pathobiology of injury to the nervous system, and the papers and reviews evaluate preclinical and clinical trials targeted at improving the early management and long-term care and recovery of patients with traumatic brain injury. Journal of Neurotrauma is the official journal of the National Neurotrauma Society and the International Neurotrauma Society. Complete tables of content and a sample issue may be viewed on the Journal of Neurotrauma website.

About the Publisher

Mary Ann Liebert, Inc. is a global media company dedicated to creating, curating, and delivering impactful peer-reviewed research and authoritative content services to advance the fields of biotechnology and the life sciences, specialized clinical medicine, public health and policy, and technology and engineering. For further information, please visit the Mary Ann Liebert, Inc. website.

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