News Release

Identifying risk factors for native coronary atherosclerosis progression after percutaneous coronary intervention

Peer-Reviewed Publication

Compuscript Ltd

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at investigating factors influencing the progression of native coronary atherosclerosis after percutaneous coronary intervention (PCI).

A cohort of 462 patients was classified into progressive (n = 73) or non-progressive (n = 389) groups according to the presence of native coronary atherosclerosis progression on coronary angiography. Clinical data and angiography results were compared during follow-up, and the time to progression of native coronary atherosclerosis was recorded. Subsequently, multivariate Cox regression analysis was conducted.

In comparison to the non-progressive group, the progressive group had higher levels of glycosylated hemoglobin (HbA1c) and triglycerides (TG), and higher scores on the Synergy Between PCI with Taxus and Cardiac Surgery (SYNTAX) scale, but lower levels of high-density lipoprotein cholesterol. Moreover, the rates of hyperuricemia and acute coronary syndrome (ACS) were higher in the progressive group than the non-progressive group. Multivariate analysis identified ACS, HbA1c level ≥6.5%, TG level ≥5.6 mmol/L, and SYNTAX score ≥23 as risk factors for the progression of native coronary atherosclerosis.

ACS, elevated HbA1c and TG levels, and higher SYNTAX scores may be associated with the progression of native coronary atherosclerosis after PCI.

CVIA is available on the ScienceOpen platform and at Cardiovascular Innovations and Applications. Submissions may be made using ScholarOne Manuscripts. There are no author submission or article processing fees. Cardiovascular Innovations and Applications is indexed in the EMBASE, EBSCO, ESCI, OCLC, Primo Central (Ex Libris), Sherpa Romeo, NISC (National Information Services Corporation), DOAJ, Index Copernicus, Research4Life and Ulrich’s web Databases. Follow CVIA on Twitter @CVIA_Journal; or Facebook.

Jianbing Wang and Zhiyu Ling. Identifying Risk Factors for Native Coronary Atherosclerosis Progression After Percutaneous Coronary Intervention. CVIA. 2024. Vol. 9(1). DOI: 10.15212/CVIA.2024.0033

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