Bentham Science has announced the release of its newest title Organoid Technology: Disease Modelling, Drug Discovery, and Personalized Medicine, a pioneering study that captures the transformative role of organoid systems in advancing human health research.
Organoids are miniature, three-dimensional in vitro models that closely replicate the structure, cellular composition, and functional behavior of real human organs. Developed from stem cells or organ-specific progenitor cells, they self-organize into complex structures that mimic key biological processes of their full-sized counterparts. This remarkable resemblance makes organoids an invaluable tool in biomedical research, as they provide a more accurate and physiologically relevant model than traditional two-dimensional cell cultures.
This book provides an in-depth exploration of organoid bioengineering, spanning the use of pluripotent and adult stem cells to create organ-specific models for a wide range of organs, including the brain, lung, kidney, liver, colon, and retina.
With its blend of foundational science and cutting-edge innovation, this title guides readers through the latest breakthroughs ranging from patient-derived tumor organoids for personalized cancer care to large-scale production protocols supported by advanced tools like 3D printing, microfluidics, genome editing, and single-cell transcriptomics. The book also addresses critical ethical, regulatory, and scalability challenges, offering a balanced perspective on the road toward reducing reliance on animal testing.
Access the book here: http://bit.ly/4mEwo9d
For review copies, interviews, or media inquiries, please contact Bentham Science Publishers.
About the Editor:
Dr. Manash K. Paul is an internationally recognized expert in stem cells, organoid systems, and cancer biology. He currently serves as Associate Professor at the Manipal School of Life Sciences, Manipal Academy of Higher Education (MAHE), India. Prior to this, he spent nearly 14 years at the University of California, Los Angeles, USA, where he worked in multiple capacities including Scientist Faculty. His research spans regenerative medicine, drug discovery, immune-oncology, and lung cancer, with significant contributions to organ-on-a-chip platforms.
Dr. Paul’s achievements include the prestigious AAISCR-R Vijayalaxmi Award for Innovative Cancer Research, UCLA Vice Chancellor’s Award, Editor’s Choice Award from Annals of Biomedical Engineering, and the BSCRC Travel Award. With over 75 publications and active memberships in multiple scientific societies, he continues to shape the future of human biology-based research.