Electronic nose sniffs out beauty breakthrough: CHARMS™ skincare antioxidant power and skin tone boost verified

The human skin serves as the first line of defense against external insults, including ultraviolet (UV) radiation, pathogens, and environmental stressors. Maintaining its integrity is essential for both functional protection and aesthetic appearance. In recent years, consumer demand for skincare cosmetics has increased substantially, with a strong focus on formulations that not only beautify but also improve skin health. Among the most sought-after effects are antioxidant protection, skin tone improvement, and skin-lightening properties. These functions are particularly important in preventing oxidative stress-induced damage, pigmentation disorders, and premature aging.

The present study focused on CHARMS™, a Malaysian cosmetic brand founded in 2012 that incorporates natural bioactive compounds into its skincare formulations. The product line investigated included cleanser, toner, essence, serum, moisturizer, scrub, and night cream. Each of these products was designed to contribute uniquely to skin maintenance and enhancement. The study was structured to evaluate two central aspects: (i) the antioxidant potential of CHARMS™ products and (ii) the presence of volatile organic compounds (VOCs), which may contribute to skin tone modulation.

For antioxidant evaluation, three complementary assays were conducted: the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging test, total phenolic content (TPC), and total flavonoid content (TFC). Results revealed that the serum and cleanser demonstrated the most potent free radical scavenging activities, suggesting their significant contribution to neutralizing reactive oxygen species. Meanwhile, the moisturizer exhibited the highest phenolic content, and the cleanser displayed the richest flavonoid profile. These antioxidant components are essential for reducing oxidative stress, which plays a key role in hyperpigmentation and skin aging.

To investigate VOCs, an electronic nose coupled with gas chromatography (e-nose-GC) was employed. The analysis identified bioactive compounds such as limonene and γ-terpinene, both of which have been associated with skin-lightening effects. These VOCs may act through the inhibition of melanogenesis and the reduction of oxidative damage, thereby contributing to overall improvement in skin appearance.

A clinical trial involving 20 female volunteers further validated the efficacy of CHARMS™ skincare products. Using a colorimeter, the study demonstrated measurable improvements in skin lightness by 3.23% and reductions in skin redness by 5.75% after product application. These changes reflect enhanced skin tone uniformity and reduced pigmentation, aligning with consumer expectations for visible cosmetic benefits.

Importantly, the study also highlighted that all CHARMS™ products complied with the regulatory standards of the Control of Cosmetic Products in Malaysia, ensuring product safety for routine use.

In summary, the investigation established a scientific foundation for the cosmetic claims of CHARMS™ skincare. The synergistic effects of antioxidants and VOCs contributed to measurable improvements in skin tone and overall skin health. These findings provide not only reassurance for consumers but also new insights into the potential dermatological applications of antioxidant-rich cosmetics. By addressing both safety and efficacy, this study supports the broader integration of CHARMS™ products into daily skincare regimens and contributes to the growing evidence base for natural ingredient-based cosmetics.