About The Study: Within the studied participants, there were clear absolute benefits of sodium-glucose cotransporter 2 (SGLT2) inhibitors on kidney, hospitalization, and mortality outcomes irrespective of diabetes status and level of urine albumin to creatinine ratio.
Corresponding Author: To contact the corresponding author, William G. Herrington, MD, email will.herrington@ndph.ox.ac.uk.
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(doi:10.1001/jama.2025.20835)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Media advisory: This study is being presented at the American Society of Nephrology Kidney Week 2025 meeting.
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Journal
JAMA