News Release

Postpandemic recovery of case mix index and risk-adjusted mortality in US hospitals

JAMA Network Open

Peer-Reviewed Publication

JAMA Network

About The Study: In this cohort study of 715 U.S. hospitals from 2019 to 2024, risk-adjusted in-hospital mortality declined significantly following the COVID-19 pandemic, resuming its prepandemic trajectory of improvement, while patient acuity as measured by case mix index remained elevated. These findings suggest a new postpandemic baseline for patient acuity, whereas hospital mortality outcomes have returned to prior improvement trends. 

Corresponding Author: To contact the corresponding author, Alyssa Harris, MPH, email alyssa.harris@vizientinc.com.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2025.43398)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 


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