image: Socioeconomic burden of age-related diseases in China
Credit: HIGHER EDUCATON PRESS
China’s rapidly ageing society—487 million people ≥ 60 years by 2050—faces an escalating dementia crisis: 15 million patients already account for one-quarter of the global total, while combined dementia and mild cognitive impairment affect 54 million citizens. Deaths from Alzheimer’s disease have risen 140% in two decades, making it a top-six cause of mortality, and annual care costs are projected to surge from US $168 billion in 2015 to US $1.9 trillion by 2050. Care-giver burden is equally stark: 84 % report sleep disturbance and 44% anxiety, while 77% of patients depend solely on unpaid family support. Current prevention and control systems, however, remain fragmented and under-resourced. Diagnosis is missed in 86% of community cases—well above the global 75%—and only 660 memory clinics operate nationwide against a need for > 3 500. Drug development lags behind the West; beyond the controversial anti-amyloid antibodies aducanumab, lecanemab and donanemab, China offers only the investigational TCM-derived GV-971. No national long-term care insurance equivalent to Japan’s or Germany’s exists, leaving families to shoulder more than half of total costs.
To close these gaps, a four-pillar framework is proposed. First, create a State-Council-led China Dementia Prevention and Control Coordination Committee uniting health, science, education, civil affairs and medical-security departments, complemented by a Chinese Alzheimer’s Disease Association under the China Association for Science and Technology and a National Alzheimer’s Disease Center jointly run by the National Health Commission and TCM Administration. Second, build a three-level technical network: community-based cognitive screening integrated into annual physical exams, standardised memory clinics in every tertiary hospital equipped with diagnostic technology and TCM protocols, and specialised long-term care facilities supported by caregiver training and respite services. Third, launch a national dementia science-and-technology programme prioritising AI-enabled early detection devices, novel drug discovery, drug-repurposing trials, validation of TCM formulas, and non-pharmacological interventions such as qigong, music therapy and smart cognitive-training tools. Finally, strengthen policy safeguards by adding dementia to the chronic-disease management package, revising the National Essential Medicines List to secure supply and insurance coverage of dementia drugs, establishing an online patient registry for real-time surveillance, and expanding medical insurance to cover long-term and end-stage care.
Implementing these measures would yield a Chinese-style dementia care system that lowers under-diagnosis, expands specialist access, accelerates innovation and relieves family burden, thereby protecting national health and social sustainability.
Journal
Frontiers of Medicine
Method of Research
Experimental study
Subject of Research
Not applicable
Article Title
Perspective on strengthening dementia prevention and control system: a comprehensive framework for national health
Article Publication Date
5-Oct-2025