About The Study: In this randomized clinical trial, a ketogenic diet had antidepressant benefits compared with a well-matched control diet at 6 weeks. However, the clinical relevance is uncertain, as the mean effect size compared with the control was modest and not evident in secondary analyses.
Corresponding Author: To contact the corresponding author, Min Gao, PhD, email min.gao@phc.ox.ac.uk.
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(10.1001/jamapsychiatry.2025.4431)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Journal
JAMA Psychiatry