About The Study: In the systematic review and meta-analysis of prospective settings, AI systems perform at comparable levels to dermatologists for melanoma diagnostics and may enhance performance when used as a decision-support tool. However, the frequent risk of bias and limited generalizability of current studies highlight the need for broader validation in unselected patient populations in the clinical setting.
Corresponding Author: To contact the corresponding author, Titus J. Brinker, MD, email titus.brinker@dkfz.de.
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(doi:10.1001/jamadermatol.2026.0217)
Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.
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Journal
JAMA Dermatology