Cancer phylogenetic inference using copy number alterations detected from DNA sequencing data

Highlights

• Phylogenetic trees built with copy number alterations are important for understanding the evolution of cancers.

• Reconstructing phylogenetic trees with copy number alterations is challenging.

• A phylogenetic tree can be built using only copy number alterations or by integrating them with other somatic variants.

• Efficient and accurate phylogenetic inference can aid oncological research and offer insights into cancer treatment.