News Release

Gestational Exposure to 10 Classes of Priority Chemicals and Birth Outcomes in the ECHO Cohort

JAMA Network Open

Peer-Reviewed Publication

JAMA Network

About The Study: This large cohort study of diverse U.S. pregnancies found widespread exposure to 10 classes of environmental chemicals, many of which were associated with differences in gestational age at birth or lower birth weight-for-gestational age scores. These findings indicate that reducing gestational exposure to chemicals, particularly phthalates or alternative plasticizers and polycyclic aromatic hydrocarbons, could promote healthy deliveries and better child outcomes.

Corresponding Authors: To contact the corresponding authors, email Jessie P. Buckley, PhD, MPH, (Jessie.Buckley@unc.edu) and Tracey J. Woodruff, PhD, MPH, (traceyw@stanford.edu).

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jamanetworkopen.2026.18883)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.


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