(Vienna, October 23, 2018) Colorectal cancer (CRC) incidence rates across Europe in adults aged 20 to 39 years increased by 6% every year between 2008 and 2016, new research has shown.
Data from 20* European national cancer registries was used to analyse trends in incidence rates of young adults with CRC across Europe over the last 25 years. For colon cancer, incidence rates increased by 1.5% per year between 1990-2008 and, more substantially, by 7.4% annually between 2008-2016. For rectal cancer, incidence rates increased by 1.8% per year from 1990-2016.
In adults aged 40 to 49 years, overall CRC incidence rates increased by 1.4% every year from 2005.
Presenting the research for the first time at UEG Week Vienna 2018, Dr Fanny Vuik explained, "We are aware of investigations in the North American population that demonstrates that colorectal cancer is increasing in young adults. In Europe, however, information until now has been limited and it's worrying to see the startling rates at which colorectal cancer is increasing in the young."
Traditionally considered a disease that affects people over the age of 50, CRC is the second most common cancer across Europe, with approximately 500,000 new cases every year and incidence rates higher in men than women. Studies have found that young-onset CRC is often more aggressive and more likely to be diagnosed at an advanced stage than CRC in older populations.
"The cause for this upward trend is still unknown, although it may be related to increasingly sedentary lifestyles, obesity and poor diets, all of which are known colorectal cancer risk factors", added Dr Vuik. "Increased awareness and further research to elucidate causes for this trend are needed and may help to set up screening strategies to prevent and detect these cancers at an early and curable stage."
Strong evidence supports that screening for CRC reduces incidence and mortality rates, although many CRC screening programmes in Europe commence at the ages of 50 and 55. Inequalities in the type of screening offered, as well as participation and detection rates, are currently present throughout the continent. Dr Vuik adds, "The highest increase in incidence was found in adults between 20-29 years of age. Therefore, identifying those young adults at high risk of CRC is essential to ensuring early diagnosis and optimal patient outcomes."
* The countries included in the research were; Belgium, Catalonia, Czech Republic, Denmark, Finland, France, Germany, Greenland, Iceland, Italy, Ireland, Latvia, the Netherlands, Norway, Poland, Portugal, Slovenia, Sweden, Switzerland and the United Kingdom.
Notes to Editors
For further information, or to arrange an interview with Dr Fanny Vuik, please contact Luke Paskins on +44 (0)1444 811099 or firstname.lastname@example.org
About Dr Fanny Vuik
Dr Fanny Vuik is PhD candidate under supervision of Dr. Manon Spaander, Associate Professor in Gastroenterology at the Department of Gastroenterology and Hepatology at the Erasmus University Medical Center, Rotterdam the Netherlands.
About UEG Week
UEG Week is the largest and most prestigious gastroenterology meeting in Europe and has developed into a global congress. It attracts over 14,000 participants each year, from more than 120 countries, and numbers are steadily rising. UEG Week provides a forum for basic and clinical scientists from across the globe to present their latest research in digestive and liver diseases, and also features a two-day postgraduate course that brings together top lecturers in their fields for a weekend of interactive learning.
UEG, or United European Gastroenterology, is a professional non-profit organisation combining all the leading European medical specialist and national societies focusing on digestive health. Together, its member societies represent over 30,000 specialists, working across medicine, surgery, paediatrics, gastrointestinal oncology and endoscopy. This makes UEG the most comprehensive organisation of its kind in the world, and a unique platform for collaboration and the exchange of knowledge. To advance the standards of gastroenterological care and knowledge across the world and to reduce the burden of digestive diseases, UEG offers numerous activities and initiatives, including:
- UEG Education, the universal source of knowledge in gastroenterology, providing online and classroom courses, a huge online library and delivering the latest GI news, fostering debate and discussion
- Activity Grants, promoting and funding educational projects in the field of digestive health to advance and harmonise the training and continuing education of professionals
- UEG Journal, covering translational and clinical studies from all areas of gastroenterology
- Public Affairs, promoting research, prevention, early diagnosis and treatment of digestive diseases, and helping develop an effective health policy for Europe
- Quality of Care, European-based and English clinical practice guidelines, clinical standards, consensus, position papers and standard protocols in the field of digestive health, are available in the repository.
1. Vuik, F. et al. 2018). Increasing incidence of colorectal cancer in young adults in Europe. Presented at UEG Week Vienna, October 22, 2018.
2. ECIS - European Cancer Information System. 2018. Estimates of cancer incidence and mortality in 2018, for all cancer sites. Available here. [Accessed 18 September 2018].
3. World Journal of Gastroenterology. 2017. Colorectal cancer in young adults: A difficult challenge. Available here. [Accessed 18 September 2018].