News Release

真核细胞进化的遗传反转录子

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

<i>E. coli</i> Cells

image: This is a microscopy image of individual E. coli cells engineered to fluoresce bright blue upon successful integration of the LINE-1 retroelement into their genome. view more 

Credit: Image courtesy of Thomas E. Kuhlman.

科研人员报告了复制并将自身插入到基因组的遗传反转录子对细菌基因组的效应,有假说认为它们是真核细胞进化的因素,他们发现,这些反转录子对于生长有害,而这些反转录子的致命性被真核生物普遍存在的一种DNA修复增强;这些结果提示,在DNA修复与反转录子之间的一种相互作用可能在真核细胞的进化中施加了选择压力。

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