News Release

Lack of physical exercise during COVID-19 confinement may lead to a rise in mortality

In a review article published in Frontiers of Endocrinology, Brazilian researchers estimate a reduction of 35% in levels of physical activity and a rise of 28% in sedentary behavior in the initial months of confinement imposed by the pandemic

Peer-Reviewed Publication

Fundação de Amparo à Pesquisa do Estado de São Paulo

Lack of physical exercise during COVID-19

image: Brazilian researchers estimate a reduction of 35% in levels of physical activity and a rise of 28% in sedentary behavior in the initial months of confinement imposed by the pandemic view more 

Credit: Isabela Roque Marc

Social distancing and working from home help prevent transmission of the novel coronavirus but can be conducive to unhealthy behavior such as bingeing on fast food or spending more time in a chair or on a couch staring at a screen, and generally moving about less during the day. Scientists believe the reduction in physical activity experienced during the first few months of the pandemic could lead to an annual increase of more than 11.1 million in new cases of type 2 diabetes and result in more than 1.7 million deaths.

The estimates are presented by researchers at São Paulo State University (UNESP), Brazil, in a review article published in Frontiers in Endocrinology. The authors stress that there is an "urgent need" to recommend physical activity during the pandemic.

"Recent studies have shown that people with diabetes face a higher risk of developing the severe form of COVID-19, and of dying if the condition is not properly controlled. Others have shown that social distancing and confinement have considerably reduced levels of physical activity, increased sedentary behavior and lowered the quality of people's nutrition. Our article serves as a warning about the harmful consequences of these trends," said Emmanuel Gomes Ciolac, a professor at UNESP's Department of Physical Education in Bauru, and principal investigator for the study.

The first author of the article is Isabela Roque Marçal, who is studying for a master's degree at UNESP. She was previously a research intern at the University of Leuven, Belgium, with a scholarship from FAPESP.

Among other data sources, the review covers the findings of an international online survey conducted by a group of 35 research institutions on several continents. According to the results, which are preliminary in that they refer to the first 1,000 volunteers to complete the questionnaire, the level of physical activity decreased 35% in the initial months of confinement, and this was accompanied by a 28.6% increase in sedentary behavior, such as sitting or lying for long periods, and unhealthy eating. Previous studies had already shown that a lack of physical activity helped cause some 33 million cases of type 2 diabetes in 2019 and 5.3 million deaths in 2018.

Based on data for the period before the pandemic, the researchers estimated that the current prevalence of physical inactivity (not getting the minimum amount of exercise recommended by health authorities) was 57.3% among over-forties generally and 57.7% among people at risk for diabetes, so that a lack of exercise can be considered responsible for 9.6% of diabetes cases (11.1 million) and 12.5% of all-cause deaths worldwide (1.7 million) if this prevalence persists for a long time.

Exercising at home

"It's important to be aware of the difference between insufficient levels of physical activity and sedentary behavior," Ciolac said. "An insufficiently active person is an individual who doesn't get the minimum amount of exercise recommended by the World Health Organization." The WHO recommends at least 150 minutes of moderate aerobic exercise or 75 minutes of vigorous aerobic exercise per week for adults aged 18-64.

Sedentary behavior, he continued, is associated with the time spent sitting, reclining or lying down. Research shows that watching television or working at a computer for long hours can be bad for the health of even physically active people. Those who are required to use a computer all day for their work should get up every 30 minutes or so to stretch their legs and get whatever light exercise is possible.

Confinement should not prevent people from performing more intense physical activity. The WHO's recommendations, for example, include taking online exercise classes, many of which are free of charge, playing with children, doing household chores such as cleaning and gardening, going up and down stairs, even walking on the spot.

The UNESP group also recommend exercises using body weight to improve muscle tone, such as situps, pushups, squatting, and standing up from a chair, as well as aerobic exercises that can safely be performed near the home, such as walking, jogging and cycling. Meals should be as healthy as possible, with plenty of vegetables and fruit, avoiding processed foods.


About São Paulo Research Foundation (FAPESP)

The São Paulo Research Foundation (FAPESP) is a public institution with the mission of supporting scientific research in all fields of knowledge by awarding scholarships, fellowships and grants to investigators linked with higher education and research institutions in the State of São Paulo, Brazil. FAPESP is aware that the very best research can only be done by working with the best researchers internationally. Therefore, it has established partnerships with funding agencies, higher education, private companies, and research organizations in other countries known for the quality of their research and has been encouraging scientists funded by its grants to further develop their international collaboration. You can learn more about FAPESP at and visit FAPESP news agency at to keep updated with the latest scientific breakthroughs FAPESP helps achieve through its many programs, awards and research centers. You may also subscribe to FAPESP news agency at

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