News Release

Rising antiparasitic drug cost in U.S. leads to higher patient costs, decreased quality of care

Rural areas have higher prevalence of the diseases that use these drugs for treatment

Peer-Reviewed Publication


New study finds the skyrocketing cost of drugs in U.S. used to treat hookworm and other soil-transmitted parasites increases patient costs, suggests decreased quality of care

A new study finds that the increasingly high prices in the United States of the drugs used to treat three soil-transmitted helminth infections--hookworm, roundworm (ascariasis), and whipworm (trichuriasis)--is not only the major driver for the increase in costs to patients with either Medicaid or private insurance, but it also may have a damaging impact on the quality-of-care patients receive as clinicians shift their prescribing patterns to more affordable yet less-effective medicines covered by insurance.

The drugs of choice recommended by the Centers for Disease Control for treating these infections--albendazole and mebendazole--have seen some of the highest price increases of drugs on the U.S. market. There are limited alternative drugs available.

The peer-reviewed study was published this week in the American Journal of Tropical Medicine and Hygiene (AJTMH) by a team of social scientists and infectious disease experts at the U.S. Centers for Disease Control (CDC), the University at Albany - SUNY, Northeastern University, HealthPartners Institute, and the University of Minnesota.

The researchers reported that "the percentages of patients prescribed the appropriate standard of care treatment with private insurance for all three infections during the study period was consistently less than 70%, and in the case of hookworm diagnosed in those with private insurance, less than 30% of patients received the standard of care prescription drug. This rate of appropriate treatment is disturbingly low. "

While these neglected parasitic worm infections are relatively uncommon across the U.S., there are pockets where the diseases are more prevalent, particularly rural areas with limited plumbing and poor sanitation. A study published in 2017 in AJTMH found that more than one in three people sampled in a poor area of Alabama tested positive for traces of hookworm, a gastrointestinal parasite though to have been eradicated from the U.S. decades ago.


?? Please contact Bridget DeSimone if you have any questions or would like to speak with the corresponding author of this latest report. ?

About the American Society of Tropical Medicine and Hygiene

The American Society of Tropical Medicine and Hygiene, founded in 1903, is the largest international scientific organization of experts dedicated to reducing the worldwide burden of tropical infectious diseases and improving global health. It accomplishes this through generating and sharing scientific evidence, informing health policies and practices, fostering career development, recognizing excellence, and advocating for investment in tropical medicine/global health research. For more information, visit

About the American Journal of Tropical Medicine and Hygiene

Continuously published since 1921, AJTMH is the peer-reviewed journal of the American Society of Tropical Medicine and Hygiene, and the world's leading voice in the fields of tropical medicine and global health. AJTMH disseminates new knowledge in fundamental, translational, clinical and public health sciences focusing on improving global health.

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