News Release

中和小鼠体内寨卡病毒的抗体

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

Structure of Mature Flaviviruses

image: Structure of mature flaviviruses. Surface view of mature ZIKV showing the E proteins arranged in a herringbone pattern. The three E protomers within one icosahedral asymmetric unit are shown in blue, red and green. Three E dimers form a raft. view more 

Credit: Image courtesy of Feng Long.

一项关于鼠科模型的寨卡病毒的研究发现,当小鼠注射一剂寨卡-195这种中和单克隆抗体之后,在病毒暴露的5天后产生了针对该病毒的防护;这组作者说,这些发现提示,寨卡-195交联了对于病毒和细胞膜融合具有关键作用的病毒外壳蛋白质,这反过来又会中和寨卡病毒。

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