News Release

分析方法识别出熊唾液中的抗生素

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

A Fossil Trilobite from the Cambrian Sirius Passet Fossil Lagerstätte of North Greenland

image: A fossil trilobite from the Cambrian Sirius Passet fossil Lagerstätte of North Greenland. view more 

Credit: Image courtesy of Jakob Vinther (University of Bristol, Bristol, United Kingdom).

根据一项研究,科研人员使用一种超高通量微流体液滴平台筛选了西伯利亚棕熊(Ursus arctos collaris)的口腔微生物组,他们识别出了短小芽孢杆菌(Bacillus pumilus)菌株产生了抗生素amicoumacin A,它能杀死病原细菌金黄色酿脓葡萄球菌(Staphylococcus aureus);这种基于液滴的方法也帮助发现芽孢杆菌抵抗这种抗生素的一种机制;这提示这个平台可用于发现新的抗生素以及筛查抗生素耐药性。

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