News Release

New research supporting stroke rehabilitation

Peer-Reviewed Publication


Using world-leading research methods, the team of Dr David Wright and Prof Paul Holmes, working with Dr Jacqueline Williams from the Victoria University in Melbourne, studied activity in an area of the brain responsible for controlling movements when healthy participants observed a video showing simple hand movements and simultaneously imagined that they were performing the observed movement.

Using transcranial magnetic stimulation - a technique where a coil placed over the scalp delivers a stimulation to the brain, activates neurons in the underlying area, and causes a muscular contraction in the participant's hand - the researchers found that combining imagery (imagining the feelings associated with performing the movement) with observation (watching the movement) created the strongest activity in the brain.

Using electrodes on the participant's hand, the researchers found that muscle contractions in response to the cortical stimulation were larger when participants were concurrently imagining themselves moving their muscle whilst watching a video of a hand moving on screen, compared to when they used the imagery or observation techniques alone. or engaged in various control conditions.

This research, which is published in the open-access journal Frontiers in Human Neuroscience, may provide useful applications for the care of stroke patients who have restricted use of their upper limbs. If stroke patients practice the recommended techniques, it could potentially help maintain activity in movement-related brain areas, especially when used alongside more traditional physiotherapy techniques where the same movements are also practiced physically.

Dr Wright said: "The idea is that because imagery and observation techniques share some characteristics with physical movement in terms of activating similar areas of the brain, if someone can't perform the movements themselves physically, it might be possible to keep those areas of the brain active through imagery and observation techniques. This might help contribute to the recovery of motor function."

Currently, imagery and, less frequently, observation are used separately alongside physical therapy during the rehabilitation of stroke patients, but Prof Holmes suggested that combining the two techniques may support re-learning of movement patterns for some patients.

He said: "After a stroke, parts of the brain die and will not recover. To compensate, other parts of brain can alter their function to take control of the lost behaviour - a form of brain plasticity. We think that combining imagery and observation, in addition to physical therapy, may allow the brain to speed up this plastic change as well as benefitting more psychological aspects of recovery such as movement confidence". He continued, "the research team's work in this area has the potential to make a real impact on the way physiotherapists, occupational therapists and nurses work with the stroke community"

"These changes may happen without the intervention - it is certainly not a miracle cure - but the combined imagery and action observation approach should speed up the process of relearning movements that have been lost."

The research was funded by Manchester Metropolitan University's Knowledge Exchange Innovation Fund and a Research Accelerator Grant awarded to Dr Wright (an early career researcher in the Motor Cognition Research section of the Centre of Health, Exercise and Active Living).

Future research by the Group will seek to establish optimal methods for delivering these psychological interventions for stroke rehabilitation by investigating the effects of different types of instruction given to participants and different video presentation methods on activity in the brain during combined imagery and observation. The team also expect to release a stroke rehabilitation App in early 2015.


Notes to editors

1. For further information, or to speak to the researchers, contact Kat Dibbits in the MMU press office on 0161 247 5278 or email

2. For online articles, please include a link to the article, which will appear on the following active URL:

Article title: Combined action observation and imagery facilitates corticospinal excitability
Journal: Frontiers in Human Neuroscience
DOI: doi: 10.3389/fnhum.2014.00951

Authors: David J. Wright, Jacqueline Williams and Paul S. Holmes

3. About Manchester Metropolitan University

Manchester Metropolitan University is a leading university for the professions and a powerful driver of the North West economy.

The University educates and trains large numbers of the region's legal and business professionals, scientists, engineers, teachers, health workers and creative professionals. It enjoys an excellent reputation for teaching and applied research and is a recognised innovator in partnership working with its local communities. The University is currently investing almost £300 million in its estate and facilities.

4. About Frontiers

Frontiers is a community-driven open-access publisher and research networking platform. Established by scientists in 2007, Frontiers drives innovations in peer-review, article level metrics, post publication review, democratic evaluation, research networking and a growing ecosystem of open-science tools. The "Frontiers in" journal series has published 25,000 peer-reviewed articles across 49 journals, which receive 6 million monthly views, and are supported by over 160,000 leading researchers worldwide. In 2014, Frontiers won the ALPSP Innovation in Publishing Award. For more information, visit:

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.