DALLAS, Sept. 24, 2019 - Cardiac MRI analysis can be performed significantly faster with similar precision to experts when using automated machine learning, according to new research published in Circulation: Cardiovascular Imaging, an American Heart Association journal.
Currently, analyzing heart function on cardiac MRI scans takes approximately 13 minutes for humans. Utilizing artificial intelligence in the form of machine learning, a scan can be analyzed with comparable precision in approximately four seconds.
Healthcare professionals regularly use cardiac MRI scans to make measurements of heart structure and function that guide patient care and treatment recommendations. Many important clinical decisions including timing of cardiac surgery, implantation of defibrillators and continuing or stopping cardiotoxic chemotherapy rely on accurate and precise measurements. Improving the performance of these measures could potentially improve patient management and outcomes.
In the UK, where the study was conducted, it is estimated that more than 150,000 cardiac MRI scans are performed each year. Based on the number of scans per year, researchers believe that utilizing AI to read scans could potentially lead to saving 54 clinician-days per year at each UK health center.
Researchers trained a neural network to read the cardiac MRI scans and the results of almost 600 patients. When the AI was tested for precision compared to an expert and trainee on 110 separate patients from multiple centers, researchers found that there was no significant difference in accuracy.
"Cardiovascular MRI offers unparalleled image quality for assessing heart structure and function; however, current manual analysis remains basic and outdated. Automated machine learning techniques offer the potential to change this and radically improve efficiency, and we look forward to further research that could validate its superiority to human analysis," said study author Charlotte Manisty, M.D. Ph.D. "Our dataset of patients with a range of heart diseases who received scans enabled us to demonstrate that the greatest sources of measurement error arise from human factors. This indicates that automated techniques are at least as good as humans, with the potential soon to be 'super-human'--transforming clinical and research measurement precision."
Although the study did not demonstrate superiority of AI over human experts and was not used prospectively for clinical assessment of patient outcomes, this study highlights the potential that such techniques could have in the future to improve analysis and influence clinical decision making for patients with heart disease.
Co-authors are Anish N Bhuva M.B.B.S.; Wenjia Bai Ph.D.; Clement Lau M.B.Ch.B..; Rhodri H. Davies Ph.D.; Yang Ye Ph.D.; Heeraj Bulluck Ph.D.; Elisa McAlindon Ph.D.; Veronica Culotta M.B.B.S.; Peter P. Swoboda Ph.D.; Gabriella Captur Ph.D.; Thomas A. Treibel Ph.D.; Joao B. Augusto M.D.; Kristopher D. Knott M.B.B.S.; Andreas Seraphim M.B.B.S.; Graham D. Cole Ph.D.; Steffen E. Petersen Ph.D.; Nicola C. Edwards Ph.D.; John P. Greenwood Ph.D.; Chiara Bucciarelli-Ducci Ph.D.; Alun D. Hughes Ph.D.; Daniel Rueckert Ph.D.; and James C. Moon M.D.
This study was funded by Barts Charity. Disclosures from the authors area available in the manuscript.
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