News Release

Investigadores del IRB Barcelona explican el origen de la misteriosa periodicidad en el genoma

Peer-Reviewed Publication

Institute for Research in Biomedicine (IRB Barcelona)

The DNA Molecule

image: The DNA molecule, formed by a double helix, winds around histone molecules twice, thus forming nucleosomes. The pink regions indicate those enriched in adenine/thymine base pairs. view more 

Credit: Author: Iris Joval Granollers

El equipo liderado por Núria López-Bigas describe en Cell qué podría haber favorecido la periodicidad de determinados pares de bases en el genoma de las especies eucariotas.

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Artículo de referencia:

Oriol Pich, Ferran Muiños, Radhakrishnan Sabarinathan, Iker Reyes-Salazar, Abel Gonzalez-Perez, Nuria Lopez-Bigas

Somatic and germline Mutation periodicity follow the orientation of the DNA minor groove around nucleosomas

Cell (2018) doi: 10.1016/j.cell.2018.10.004


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