image: MS4A4A (green) and TREM2 (red) were both localized to the plasma membrane and organelles of human macrophages. This material relates to a paper that appeared in the August 14, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by Y. Deming at Washington University School of Medicine in St. Louis, MO; and colleagues was titled, "The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk." view more
Credit: Y. Deming <i>et al., Science Translational Medicine</i> (2019)