Epigenetics may explain how Darwin's finches respond to rapid environmental change

Epigenetics may explain how Darwin's finches respond to rapid environmental changes, according to new research published in the open access journal BMC Evolutionary Biology.

By studying rural and urban populations of two species of Darwin's finches on the Galapagos Islands, researchers were able to show that while there was very little genetic variation, there were substantial epigenetic differences that could be related to environmental differences resulting from urbanization.

Sabrina McNew, PhD student at the University of Utah and lead author of the study said: "Urbanization of the Galapagos has happened relatively recently, so this is a good opportunity to study how animals respond to rapid environmental change."

Dr Michael Skinner, senior author from Washington State University, said: "In the finches that we studied, epigenetic alterations between the populations were dramatic, but minimal genetic changes where observed. We believe that the epigenetic differences may be a heritable component that might explain the rapid adaptation of Darwin's finches to an urban environment. These species of finch have distinct diets which could explain the differences in methylation patterns as diet is known to influence epigenetics. This is a novel mechanism which is not seriously considered in evolutionary biology at this time".

Epigenetics, particularly a chemical modification to DNA known as methylation, has emerged as a heritable component linked to differences between members of a population and might play a role in the molecular basis of evolutionary change. DNA methylation can be induced by the environment and can impact gene expression, leading to changes in physical traits such as size.

Sabrina McNew explained: "We can't say for sure how these methylation differences affect the morphology or physiology of the finches; however, it's exciting to document epigenetic variation on a population-level. This project is a first step in understanding if epigenetic changes are involved in adaptation to changing environments."

In this study, the authors captured over 1,000 birds of two species of Darwin's finch, the medium ground finch (Geospiza fortis) and the small ground finch (G. fuliginosa), from a rural and an urban site located 10km apart on the Galapagos Islands. Morphological study of the birds revealed that G. fortis from the urban environment were larger in all measured traits than their rural counterparts. There were no size differences recorded between the urban and rural G. fuliginosa, which could be due to the fact that the two species have different diets and because G. fuliginosa are less variable in size than G fortis, according to the researchers.

Genetic analysis of the birds revealed very little differences in genetic make-up between the rural and urban populations of both species. Analysis of DNA methylation patterns revealed significant differences between urban and rural populations for both species.

This study compared just two populations of finches so it cannot be said with certainty that urbanization is the key influencer of epigenetics or morphology. However the results are consistent with a potential role of epigenetic variation in rapid adaptation to changing environments. Future studies are needed to determine what direct effects DNA methylation has on physical traits, and to what extent these methylation patterns may play a role in evolution.

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Notes to editor:

1. Images of the two finch species from this study can be found here: https://goo.gl/raXn1N

Please credit: McNew et al., BMC Evolutionary Biology, 2017

2. Research article:

Epigenetic variation between urban and rural populations of Darwin's finches McNew et al.
BMC Evolutionary Biology August 2017

DOI: 10.1186/s12862-017-1025-9

During embargo period, please contact Matthew Lam for a copy of the article.

After the embargo lifts, the article will be available at the journal website here: https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-017-1025-9

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3. BMC Evolutionary Biology is an open access, peer-reviewed journal that considers articles on all aspects of molecular and non-molecular evolution of all organisms, as well as phylogenetics and palaeontology.

4. A pioneer of open access publishing, BMC has an evolving portfolio of high quality peer-reviewed journals including broad interest titles such as BMC Biology and BMC Medicine, specialist journals such as Malaria Journal and Microbiome, and the BMC series. At BMC, research is always in progress. We are committed to continual innovation to better support the needs of our communities, ensuring the integrity of the research we publish, and championing the benefits of open research. BMC is part of Springer Nature, giving us greater opportunities to help authors connect and advance discoveries across the world.

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