PHOENIX, March 3, 2020 -- Sleeping well, long enough and having regular bedtimes, in addition to meeting the American Heart Association's Life's Simple 7 guidelines, may help reduce the risk of heart attacks, strokes and other cardiovascular diseases. Improved sleep patterns may also help people achieve and maintain a healthier body weight, according to preliminary research presented in two studies at the American Heart Association's Epidemiology and Prevention | Lifestyle and Cardiometabolic Health Scientific Sessions 2020. The EPI Scientific Sessions, March 3-6 in Phoenix, is a premier global exchange of the latest advances in population-based cardiovascular science for researchers and clinicians.
Mounting scientific evidence shows sleep problems are associated with a higher risk of developing obesity, high blood pressure, diabetes and heart disease.
The role of sleep as a cardiovascular health metric: Does it improve cardiovascular disease risk prediction? Results from the Multi-Ethnic Study of Atherosclerosis (Abstract 36)
A new study suggests that sleep should be added as an eighth metric of heart heath to the American Heart Association's Life's Simple 7 (LS7). LS7 is used by health care providers to evaluate an individual's cardiovascular health using seven metrics: tobacco use, body weight, diet, physical activity, cholesterol, blood pressure and glucose levels.
The study compared the LS7 score, to novel heart health scores that include sleep habits in addition to the already established seven metrics of heart health. Researchers found that when sleep duration, the simplest and most straightforward measure of sleep, was included as an eighth metric of heart health, the heart health score was more strongly associated with heart disease. Researchers found those who had the healthiest sleep duration (7-8 hours) during a sleep study, in addition to meeting LS7's guidelines, were 61% less likely to have a heart disease diagnosis, compared to people who had the poorest scores.
Notably, heart health scores that considered sleep behaviors such as sleeping poorly, sleeping less than seven hours or nine or more hours per night, and/or having irregular sleep duration and bedtimes, as well as sleep disorders such as sleep apnea and insomnia, showed the strongest associations with increased heart disease risk.
Those who had healthy sleep behaviors and no sleep disorders in addition to meeting the LS7 had up to 59% lower likelihood of having a heart attack, stroke, heart failure or other cardiovascular event at the time of the sleep study and up to 44% lower risk of developing heart disease 4 ½ years later.
"These findings underscore the importance of embracing a holistic vision of sleep health that includes both sleep behaviors and sleep disorders when assessing cardiovascular risk. The approach to promoting a healthy lifestyle for heart disease prevention, which traditionally focused on diet and exercise, should be expanded to include sleep," said lead study author Nour Makarem, Ph.D., an associate research scientist at Columbia University's Vagelos College of Physicians and Surgeons in New York City.
"The American Heart Association is monitoring the science associated with sleep and stress, and we welcome new research on the health effects of quality sleep," said the American Heart Association's Chief Medical Officer for Prevention and Chief of the Center for Health Metrics and Evaluation Eduardo Sanchez, M.D., M.P.H., FAAFP. "This study adds to the knowledge base, and we will continue to watch closely as the body of evidence on sleep and cardiovascular disease builds. It may soon be time to add sleep to Life's Simple 7. We could call it Life's Essential 8."
The study participants included 1,920 adults, with an average age of 69, from the Multi-Ethnic Study of Atherosclerosis (MESA) Study, a longitudinal study on cardiometabolic risk factors. Participants from six centers took part in a 7-day sleep exam and were followed for an average of 4 ½ years.
Co-authors of the study are Cecilia Castro-Diehl, Ph.D.; Marie-Pierre St-Onge, Ph.D.; Susan Redline, M.D.; M.P.H.; Steven Shea, M.D., M.S.; Donald M. Lloyd-Jones, M.D., Sc.M.; Hongyan Ning, M.D., M.S.; and Brooke Aggarwal, Ed.D., M.S. Author disclosures are in the abstract. This study was funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health.
Impact of change in bedtime variability on body composition: Secondary findings from the Go Red for Women Strategically Focused Research Network (Abstract MP19)
Women who went to bed at the same time every day lost about two pounds of body fat over a 6-week period, compared to women who had greater variations in their day-to-day bedtimes, even though both groups of women slept the same amount of time, according to new research.
The study included 37 women, ages 22 to 46, whose body weight was either normal or overweight but not obese, at the start of the study. Two weeks before the intervention arm of the study began, the women wore devices on their wrist to measure bedtimes and sleep duration, which ranged from 7 to 9 hours.
Over separate 6-week periods, the women's sleep duration and bedtimes were compared to the prior 2-weeks. While the number of hours each woman slept did not change, 29 women improved their sleep regularity - adopting a more consistent bedtime. This decreased bedtime variability was associated with weight loss.
"This improvement in body composition occurred without any recommendations for weight loss or tips to change their diet, eating or exercise - all they did was sleep on a more consistent schedule," said lead study author Marie-Pierre St-Onge, Ph.D., M.Sc., FAHA, associate professor of nutritional medicine and director of the Sleep Center of Excellence at Columbia University Irving Medical Center in New York City, and writing group chair for the American Heart Association's 2016 Scientific Statement Sleep Duration and Quality: Impact on Lifestyle Behaviors and Cardiometabolic Health.
"If your bedtimes are more stable, that means your circadian rhythms are more stable. There's less potential for circadian misalignment, which has been shown to be associated with increased risk of obesity and cardiometabolic risk factors," said St-Onge. "The key message is that people should try to go to bed at consistent times every night and wake up at the same time every morning." Circadian rhythm refers to the 24-hour cycle of when we are awake, asleep, hungry, tired or energetic and is tied to daylight and the darkness of night.
This sleep study is part of an ongoing study on the role of sleep restriction on cardio-metabolic risk factors, such as body weight, insulin resistance, glucose metabolism and others. The study is limited because of the small number of participants and further research is needed to determine if these findings are generalizable to other people.
Co-authors are Ayanna Campbell, M.S.; Faris Michael Zuraikat, Ph.D.; and Bin Cheng, Ph.D. Author disclosures are in the abstract. This study was funded by the Go Red for Women Strategically Focused Research Network of the American Heart Association.
Downloadable multimedia related to this news release is on the right column of the link https://newsroom.heart.org/news/better-sleep-habits-may-help-reduce-heart-disease-risk-and-aid-in-weight-loss?preview=136013c73a09f4393e278d87a008b1e9
American Heart Association News Release: Sleeping Less Than Six Hours and Heart Disease, Stroke - Deadly Combo
American Heart Association News Release: Insomnia Tied to Higher Risk of Heart Disease and Stroke
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Statements and conclusions of study authors that are presented at American Heart Association scientific meetings are solely those of the study authors and do not necessarily reflect Association policy or position. The Association makes no representation or warranty as to their accuracy or reliability. The Association receives funding primarily from individuals; foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific Association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations are available at https://www.heart.org/en/about-us/aha-financial-information.
The American Heart Association's EPI | LIFESTYLE 2020 Scientific Sessions is the world's premier meeting dedicated to the latest advances in population-based science and will be held March 3-6 in Phoenix, Arizona. The four-day conference will feature nearly 600 compelling scientific presentations to promote the development and application of translational and population science to prevent heart disease and stroke and foster cardiovascular health. The theme of this year's conference is Promoting Cardiovascular Health Across the Lifespan: How Do We Live Healthier, Longer? and is presented in collaboration with the Council on Lifestyle and Cardiometabolic Health and the Council on Epidemiology and Prevention. Follow the conference on Twitter at #EPILifestyle20.
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