News Release

疟疾的耐药性突变

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

科研人员报告说，两种西非疟疾株型对青蒿素药物耐药性的体外选择产生了此前未识别出的突变，这些突变把针对青蒿素的耐药性赋予了PfCoronin基因，PfCoronin是一种保守的肌动蛋白结合蛋白，与涉及青蒿素耐药性的另一种蛋白质PfKelch13具有结构相似性，这提供了关于青蒿素耐药性的分子机制的可能的见解。

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Journal

Proceedings of the National Academy of Sciences

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