image: To study the role of Purkinje cells in essential tremor, the scientists made the cells express the light-sensing ion pump NpHR (green) in the cerebellums of mice and stimulated them with green light. This material relates to a paper that appeared in the Jan. 15, 2020, issue of Science Translational Medicine, published by AAAS. The paper, by M.-K. Pan at National Taiwan University Hospital in Taipei City, Taiwan; and colleagues was titled, "Cerebellar oscillations driven by synaptic pruning deficits of cerebellar climbing fibers contribute to tremor pathophysiology." view more
Credit: M.-K. Pan <i>et al., Science Translational Medicine</i> (2019)