image: A microsphere is cleared out from a pulmonary vessel into the surrounding space. Confocal imaging in lung tissue demonstrated a 100 μm polystyrene microsphere (red) that had extravasated out of a pulmonary vessel into the alveolar space 8 days after embolization. Although the microsphere is located next to alveolar capillaries (magenta), given its large size the authors conclude that it extravasated from a larger arteriole not visible in the image and gradually moved through the alveolar duct. This image relates to a paper that appeared in the March 5, 2014, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. J. Grutzendler at Yale University School of Medicine in New Haven, Conn., and colleagues was titled, "Angiophagy Prevents Early Embolus Washout But Recanalizes Microvessels Through Embolus Extravasation." view more
Credit: Image courtesy of <i>Science Translational Medicine</i>/AAAS