News Release

Adults with pain at greater risk for cannabis use disorder, finds study

Peer-Reviewed Publication

Columbia University Irving Medical Center

A new study from researchers at Columbia University Vagelos College of Physicians and Surgeons found that non-medical cannabis use--including frequent or problematic use--is significantly more common in adults with pain than in those without pain.

The findings were published in the American Journal of Psychiatry.

Since 1996, 34 states have passed medical marijuana laws and 11 states have legalized recreational cannabis use.

Studies indicate that heavy cannabis use increases the risk of vehicle accidents, respiratory and psychiatric symptoms, and cannabis use disorder.

"Despite this evidence, many people view cannabis use as harmless, and non-medical use of cannabis on a daily or near-daily basis has increased," says Deborah Hasin, PhD, a professor of epidemiology in the Department of Psychiatry at Columbia University Vagelos College of Physicians and Surgeons who led the current study. "In our study, we hoped to identify factors--such as pain--that may increase the risk of cannabis use disorder."

Hasin and colleagues analyzed data on marijuana use from the National Epidemiologic Surveys on Alcohol and Related Conditions in 2001-2002 and 2012-2013. The researchers compared non-medical cannabis use patterns in adults with and without pain (approximately 20% of participants in both surveys had moderate to severe pain).

Overall, non-medical marijuana use increased from about 4% in 2002 to 9.5% in 2013. In addition, in the most recent survey, those with pain were significantly more likely to engage in frequent non-medical cannabis use than those without pain (5.0% vs. 3.5%). The risk of cannabis use disorder was also significantly higher in those with pain (4.2% vs. 2.7%).

"Although meta-analyses of cannabis for treating pain show only mixed efficacy, particularly for plant marijuana, 66% of adults now view marijuana as beneficial for pain management. Given that about 20% of the adult population experienced moderate to severe pain, this puts a large group of U.S. adults at risk for frequent non-medical use and cannabis use disorder. Greater balance is needed in media reporting of marijuana issues, including messages that convey credible information about the nature and magnitude of health risks from non-medical cannabis use, including among the large group of US adults with pain," says Hasin. "Psychiatrists and other mental health professionals treating patients with pain should monitor their patients for signs and symptoms of cannabis use disorder."

The paper is titled "US adults with pain, an increasingly vulnerable group for non-medical cannabis use and cannabis use disorder: 2001-2002 and 2012-2013."


Additional authors are Dvora Shmulewitz, PhD (Columbia University Irving Medical Center, New York, NY) Magdalena Cerdá, DrPH (New York University, New York, NY); Katherine M. Keyes, PhD (CUIMC); Mark Olfson, MD, MPH (CUIMC); Aaron L. Sarvet, MPH. (Harvard University, Boston, MA); Melanie M. Wall, PhD (CUIMC).

The study is supported by the National Institute on Drug Abuse (R01DA034244 and R01DA048860, Hasin; R01DA019606, Wall and Olfson; T32 MH017119, Sarvet) and the New York State Psychiatric Institute.

Dr. Hasin reports funding from Campbell Alliance for unrelated projects on the validation and use of a measure of opioid addiction among patients with chronic pain. All other authors report no financial relationships with commercial interests.

The Columbia University Department of Psychiatry is among the top ranked psychiatry departments in the nation and has contributed greatly to the understanding and treatment of brain disorders. Co-located at the New York State Psychiatric Institute on the NewYork-Presbyterian Hospital/Columbia University Irving Medical Center campus in Washington Heights, the department enjoys a rich and productive collaborative relationship with physicians in various disciplines at the Columbia University Vagelos College of Physicians and Surgeons. Columbia Psychiatry is home to distinguished clinicians and researchers noted for their clinical and research advances in the diagnosis and treatment of depression, suicide, schizophrenia, bipolar and anxiety disorders, eating disorders, substance use disorders, and childhood psychiatric disorders.

Columbia University Irving Medical Center provides international leadership in basic, preclinical, and clinical research; medical and health sciences education; and patient care. The medical center trains future leaders and includes the dedicated work of many physicians, scientists, public health professionals, dentists, and nurses at the Vagelos College of Physicians and Surgeons, the Mailman School of Public Health, the College of Dental Medicine, the School of Nursing, the biomedical departments of the Graduate School of Arts and Sciences, and allied research centers and institutions. Columbia University Irving Medical Center is home to the largest medical research enterprise in New York City and State and one of the largest faculty medical practices in the Northeast. For more information, visit or

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