News Release

抗病毒蛋白把肠道微生物群与过敏联系起来

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

科研人员报告说,与野生型小鼠相比,遗传缺乏一种线粒体抗病毒蛋白(MAVS)的小鼠遇到了肠道微生物群的显著改变,这个疾病称为菌群失调,这导致了炎症挑战情况下的肠道通透性的增加与细菌在体内的迁移,以及人类过敏接触性皮炎的鼠类模型的易感性增加;这些结果提示了在肠道微生物群与过敏之间存在一种机制联系。

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