video: This is a calcium-dependent fluorescence recording of neurons that have not (left) or have been (right) heat-sensitized with the capsaicin receptor TRPV1. When neurons are excited with an alternating magnetic field ('ON'), evoked activity captured by fluorescence spiking in the video is observed. As neural activity diminishes between 'ON' cycles, another magnetic field pulse is applied for re-excitation. Movie is 5.4 times faster than real time. This material relates to a paper that appeared in the March 13, 2015 issue of Science, published by AAAS. The paper, by Ritchie Chen at the Massachusetts Institute of Technology in Cambridge, MA, and colleagues was titled, "Wireless Magnetothermal Deep Brain Stimulation." view more
Credit: [Credit: Ritchie Chen and Polina Anikeeva]