News Release

Choir singing boosts immune system activity in cancer patients and carers, study shows

Singing in a choir for just 1 hour causes physiological changes in people affected by cancer

Peer-Reviewed Publication


Choir Singing May Modulate Immune Systems of Cancer Patients

video: Singing in a choir for just one hour boosts levels of immune proteins in people affected by cancer, reduces stress and improves mood, which in turn could have a positive impact on overall health, a new study by Tenovus Cancer Care and the Royal College of Music published today in ecancermedicalscience has found. Professor Gordon McVie and Dr. Ian Lewis explain the science behind the study, while a patient explains her experiences. You can watch a clip of the choir as well! view more 

Credit: Andy Williams, Tenovus Cancer Care

Singing in a choir for just one hour boosts levels of immune proteins in people affected by cancer, reduces stress and improves mood, which in turn could have a positive impact on overall health, a new study by Tenovus Cancer Care and the Royal College of Music published today in ecancermedicalscience has found.

The research raises the possibility that singing in choir rehearsals could help to put people in the best possible position to receive treatment, maintain remission and support cancer patients.

The study tested 193 members of five different choirs. Results showed that singing for an hour was associated with significant reductions in stress hormones, such as cortisol, and increases in quantities of cytokines - proteins of the immune system - which can boost the body's ability to fight serious illness.

Dr Ian Lewis, Director of Research and Policy at Tenovus Cancer Care and co-author of the research, said: "These are really exciting findings. We have been building a body of evidence over the past six years to show that singing in a choir can have a range of social, emotional and psychological benefits, and now we can see it has biological effects too.

"We've long heard anecdotal evidence that singing in a choir makes people feel good, but this is the first time it's been demonstrated that the immune system can be affected by singing. It's really exciting and could enhance the way we support people with cancer in the future."

The study also found that those with the lowest levels of mental wellbeing and highest levels of depression experienced greatest mood improvement, associated with lower levels of inflammation in the body. There is a link between high levels of inflammation and serious illness.

Choir members gave samples of their saliva before an hour of singing, and then again just after. The samples were analysed to see what changes occurred in a number of hormones, immune proteins, neuropeptides and receptors.

Dr Daisy Fancourt, Research Associate at the Centre for Performance Science, a partnership between the Royal College of Music and Imperial College London and co-author of the research, said: "Many people affected by cancer can experience psychological difficulties such as stress, anxiety and depression. Research has demonstrated that these can suppress immune activity, at a time when patients need as much support as they can get from their immune system. This research is exciting as it suggests that an activity as simple as singing could reduce some of this stress-induced suppression, helping to improve wellbeing and quality of life amongst patients and put them in the best position to receive treatment."

Diane Raybould, 64, took part in the study and has been singing with the Bridgend Sing with Us choir since 2010. Diane was diagnosed with breast cancer when she was aged 50. Her daughter was diagnosed with breast cancer at the same time and sadly, passed away from the disease at just 28. Diane said: "Singing in the choir is about more than just enjoyment, it genuinely makes you feel better. The choir leaders play a huge part of course, but so does the support of the other choir members, the inspirational programme and uplifting songs. The choir is a family, simple as that. Having cancer and losing someone to cancer can be very isolating. With the choir, you can share experiences openly and that is hugely important."

Rosie Dow, Head of Sing with Us at Tenovus Cancer Care and co-author of the research, added: "This research is so exciting, as it echoes everything all our choir members tell us about how singing has helped them. I've seen peoples' lives transformed through singing in our choirs so knowing that singing also makes a biological difference will hopefully help us to reach more people with the message that singing is great for you - mind, body and soul."

Following on from this research, Tenovus Cancer Care is launching a two year study looking in more depth at the longitudinal effect of choir singing over several months. It will look at mental health, wellbeing, social support and ability to cope with cancer, alongside measuring stress hormones and immune function amongst patients, carers, staff and people who have lost somebody to cancer.


The full research paper can be found at

If you or someone you love has been affected by cancer, Tenovus Cancer Care can offer help and support. To find out more call the Tenovus Cancer Care free Support Line on 0808 808 1010 or visit

For more information contact Ruth Taylor, PR and Communications Manager on 07429 103084 / Research paper available on request

About the research:

  • 193 members of five choirs in Cardiff, Bridgend, Pontypridd, Cwmbran and Swansea took part in the study across between June and July 2014.
  • The Centre for Performance Sciences is a partnership between the Royal College of Music, London and Imperial College London.
  • Tenovus Cancer Care runs 17 Sing with Us choirs across England and Wales. For more information please visit

Notes to editor:

  • At Tenovus Cancer Care our aims are simple: to help prevent, treat and find a cure for cancer. In doing that we offer support, advice and treatment, information on prevention and funding for research to improve outcomes for people living with cancer. We do this where it is needed most - right at the heart of the community.
  • Tenovus Cancer Care free Support Line is open 8am - 8pm, 365 days a year on 0808 808 1010.
  • Keep up to date with Tenovus Cancer Care by following them on Twitter @tenovuscancer or Liking their page on Facebook
  • The Royal College of Music is currently home to 800 undergraduate and postgraduate students from 60 nations. International students constitute approximately 50% of our student body. In 2016, the RCM was ranked by The Guardian as the leading Higher Education Institution in the UK for studying music. The Higher Education Statistics Agency (HESA) survey found that proportionally more RCM alumni who responded to the survey had moved to employment or further study within six months of graduation than graduates from any other UK conservatoire or UK university.
  • Among RCM alumni are composers and performers such as Sir Hubert Parry, Benjamin Britten, Gustav Holst, Sir Colin Davis, David Helfgott, Samuel Coleridge-Taylor, Lord Lloyd Webber, Dame Joan Sutherland, Sir James Galway, Ralph Vaughan Williams and Alfie Boe. Regular visitors to the RCM to teach and demonstrate are Bernard Haitink, Vladimir Ashkenazy and Lang Lang. Our most recent honorary doctorates include Vladimir Jurwoski, Dame Kiri Te Kanawa, Sir Roger Norrington, Bryn Terfel and Steve Reich.
  • The Centre for Performance Science is a distinctive new partnership of the Royal College of Music and Imperial College London. The Centre takes a strongly interdisciplinary approach to investigating human performance in the arts, business, education, medicine, science and sport, and draws upon world-leading expertise and state-of-the-art facilities across the RCM and Imperial College.
  • ecancermedicalscience is an open-access journal that is free to read.

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