News Release

International team decodes the durum wheat genome

The new genome sequence will contribute to global food safety and security

Peer-Reviewed Publication

University of Saskatchewan

Curtis Pozniak, University of Saskatchewan

image: This is Curtis Pozniak, of the University of Saskatchewan, Canada view more 

Credit: University of Saskatchewan

An international consortium has sequenced the entire genome of durum wheat--the source of semolina for pasta, a food staple for the world's population, according to an article published today in Nature Genetics.

The team has also discovered how to significantly reduce cadmium levels in durum grain, ensuring the safety and nutritional value of the grain through selective breeding.

"This ground-breaking work will lead to new standards for durum breeding and safety of durum-derived products, paving the way for production of durum wheat varieties better adapted to climate challenges, with higher yields, enhanced nutritional quality, and improved sustainability," said Luigi Cattivelli of Italy's Council for Agricultural Research and Economics (CREA).

The durum wheat genome is four times as large as the human genome. The team has for the first time assembled the complete genome of the high-quality Svevo variety.

"We can now examine the genes, their order and structure to assemble a blueprint that provides an opportunity to understand how the genes work and communicate with one another," said wheat breeder Curtis Pozniak of the University of Saskatchewan (USask). "With this blueprint, we can now work quickly to identify genes that are responsible for the traits we select for in our breeding programs such as yield, disease resistance, and nutritional properties."

The research involved more than 60 scientists from seven countries. The work was co-ordinated by Cattivelli and included corresponding authors Pozniak of USask and Klaus Mayer of the Helmholtz Zentrum in München (Germany), as well as researchers Aldo Ceriotti and Luciano Milanesi of Italy's national research council CNR and Roberto Tuberosa of the University of Bologna (Italy).

"We can now see the distinct DNA signatures that have been so critical to the evolution and breeding of durum wheat, enabling us to understand which combination of genes is driving a particular signature and to maintain those target areas of the genome for future breeding improvement," said Marco Maccaferri, lead author of the manuscript.

Durum wheat, mainly used as the raw material for pasta and couscous production, evolved from wild emmer wheat and was established as a prominent crop roughly 1,500 to 2,000 years ago in the Mediterranean area.

The team compared the durum wheat sequence to its wild relative and were able to reveal genes that humans have been selecting over the centuries. The scientists uncovered a loss of genomic diversity in durum wheat compared to its wild wheat relative, and they've been able to map these areas of loss and precisely recover beneficial genes lost during centuries of breeding.

"Unlike in humans, durum wheat is a so-called polyploid and contains two genomes. How these genomes interact and coordinate their activities is a fundamental question that might also have impact on food quality and yield," said Mayer.

In an exciting genetic discovery, Pozniak's USask team, along with University of Alberta scientists Gregory Taylor and Neil Harris, identified the gene in durum wheat responsible for accumulation of cadmium, a toxic heavy metal found in many soils.

"Now that we've identified this gene, we can effectively select varieties that do not accumulate significant cadmium in the grain--levels well below World Health Organization standards which will ensure that our durum wheat products are more nutritionally safe," said Pozniak.

Durum wheat is mainly cultivated in Canada, Europe, United States, and South Asia, and remains a key crop for small farms in North and East Africa, as well as the Middle East.

As pasta is a staple for the world's population, industries are asking for more, safer, and higher-quality durum wheat.

"Having this durum wheat high-quality genome sequence enables us to better understand the genetics of gluten proteins and the factors that control the nutritional properties of semolina. This will help to improve pasta quality traits," said Ceriotti.

"The selection of new durum cultivars with greater yield potential, as well as enhanced quality and nutritional properties, is critical for our future well-being, particularly in the face of climate change. The availability of the durum genome sequence is an essential tool to achieve these targets and provides a strategic bridge between the biodiversity of wild progenitors and bread wheat," said Tuberosa.

Funding was provided by: CREA; the Italian Ministry of Education University and Research Projects InterOmics and PON-ISCOCEM; Natural Sciences and Engineering Research Council of Canada; Genome Canada and Genome Prairie; Saskatchewan Ministry of Agriculture and Government of Canada through the Agriculture Development Fund; Western Grains Research Foundation; Saskatchewan Wheat Commission; Alberta Wheat Commission; Manitoba Wheat and Barley Growers Association; Fondazione AGER; University of Bologna; Binational Science Foundation; Israel Science Foundation; U.S. Department of Agriculture; German Federal Ministry of Food and Agriculture; and German Ministry of Education and Research.


The Nature Genetics article can be seen here:

Access to the durum wheat genome is available at: and in the scientific database GrainGenes.

For more information, contact:

CREA - Council for Agricultural Research and Economics

Cristina Giannetti
+39 0647836335

University of Saskatchewan

Jennifer Thoma
Media Relations Specialist
+1 (306) 966-1851

CNR National Research Council

Marco Ferrazzoli
+ 39 06 4993 3383

University of Bologna

Monica Lacoppola
+39 051 209 8547

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