Bottom Line: Macrovascular disease events, which include heart attack and stroke, are a leading cause of illness and death for patients with type 2 diabetes. Medical management, including lifestyle changes, may not reduce patient risk but bariatric surgery may help. In this observational study of about 20,000 patients with severe obesity and type 2 diabetes who underwent bariatric surgery or received usual medical care for diabetes, bariatric surgery was associated with a lower risk of macrovascular disease events at five years of follow-up (2.1 percent vs 4.3 percent). The findings require confirmation in randomized clinical trials.
Authors: David Arterburn, M.D., M.P.H., Kaiser Permanente Washington Health Research Institute, Seattle, and coauthors
The following related elements from the JAMA Network are also available on the For The Media website:
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-- The JAMA editorial, "Preventing Macrovascular Events With Bariatric Surgery," by Sayeed lkramuddin, M.D., M.H.A., University of Minnesota, Minneapolis, and coauthors.
-- The JAMA Surgery editorial: "Standardized Uniform Reporting and Indications for Bariatric and Metabolic Surgery," by Paulina Salminen, M.D., Turku University Hospital, Turku, Finland.
-- The JAMA study, "Comparison of the Performance of Common Measures of Weight Regain After Bariatric Surgery for Association With Clinical Outcomes," by Wendy C. King, Ph.D., University of Pittsburgh, and coauthors.
The JAMA editorial, "Setting Appropriate Expectations After Bariatric Surgery," by Amir A. Ghaferi, M.D., M.S., and Oliver A. Varban, M.D., University of Michigan, Ann Arbor.
Previously published by JAMA: Bariatric Surgery for Type 2 Diabetes
To Learn More: The full study is available on the For The Media website.
Editor's Note: The article includes conflict of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.
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