video: Calcium sparks in a smooth muscle cell isolated from the tail artery of the RYR1Y522S heterozygous knock-in mouse. This material relates to a paper that appeared in the Kuly 05, 2016, issue of Science Signaling, published by AAAS. The paper, by R.J. Lopez at Basel University Hospital in Basel, Switzerland, and colleagues was titled, "An RYR1 mutation associated with malignant hyperthermia is also associated with bleeding abnormalities." view more
Credit: Lopez et al., <i>Science Signaling</i> (2016)