video: This is a 3D animation showing the fit of the crystal structure of N (yellow ribbon) with vRNA (dark ribbon) into the cryoEM density map (semi-transparent shaded surface). The movie then zooms into the C-lobes of N’s. The conformation of N in the virion trunk versus that in the decamer ring is contrasted by morphing between the two structures. We notice that the hydrogen bonds and hydrophobic interactions observed in the side-by-side interface of N as in the decamer ring are pulled apart by ~9Å in the virion trunk. This video relates to an article that appeared in the February 5, 2010, issue of Science, published by AAAS. The study, by Dr. P. Ge at University of California, Los Angeles in Los Angeles, Calif., and colleagues, was titled, "Cryo-EM Model of the Bullet-Shaped Vesicular Stomatitis Virus." view more
Credit: Video courtesy of Dr. Z. Hong Zhou