image: Rice University chemists who discovered that chemicals used in Billups-Birch reductions of carbon nanotubes react with the white PTFE stir bars, turning them black. They recommend using glass stir bars, like the one in the middle, for such reductions. view more
Credit: Brandon Martin/Rice University
HOUSTON - (March 29, 2019) - The stirrers that mix cream into your coffee probably don't make much difference to the drink. But in a chemistry lab, it turns out using the wrong stirrer can skew the science.
Rice University scientists have determined that stir bars made of PTFE, more commonly known as Teflon, can introduce errors into a standard lab reaction used to manipulate the properties of carbon or boron-nitride nanotubes.
Stir bars are pellet-like rods of ferromagnetic metal covered in PTFE that sit in the bottom of a beaker and are turned by a rotating magnetic field. They allow a solution to be mixed in a closed flask without manual stirring.
The Rice lab of Angel Martí published a paper in the American Chemical Society journal ACS Omega outlining what happens when PTFE stir bars are used to functionalize nanotubes through Billups-Birch reduction, a long-used reaction developed in part by Rice Professor Emeritus of Chemistry Edward Billups that frees electrons to bind with other atoms.
Reduction is often used to make nanotubes more amenable to functionalization, the process of customizing them for applications by adding molecules like proteins. That can be as simple as dispersing nanotubes in a chemical bath laden with the molecules you want to add. Billups-Birch is one such method, a one-step process used to functionalize nanotubes with a variety of molecules, according to the researchers.
When they used it to modify nanotubes of boron-nitride, the researchers were surprised to see their tubes turn gray, while the PTFE stir bars turned black. Standard thermogravimetric analysis, usually adequate to see evidence of functionalization, didn't see anything wrong - but the researchers did.
"Aside from that, we couldn't get consistent results," Martí said. "Sometimes we would get very high functionalization - or apparent functionalization - and sometimes we wouldn't. That was really strange."
They found the lithium in the ammonia-based solvent used in the Billups-Birch reaction was reacting with the white PTFE from the bars, turning them black.
"Because carbon nanotubes are black, it would be easy to believe that nanotubes were depositing on the bars throughout the reaction," Martí said. "But that's not what happens. We found that in Billups-Birch conditions, the PTFE reacts.
"Teflon doesn't generally react with anything," he said. "That's why it's used in stir bars, and in cookware. That's why it's also easy to overlook what we saw happening in the lab."
Martí said search of the literature turned up nothing about avoiding PTFE in Billups-Birch.
"That was odd, too," he said. "Maybe everybody else knows - but just in case we decided to explore the problem. That's why we decided to write a paper."
The researchers suspect the unexpected reaction with Teflon is creating radicals that reduce the efficiency of the reaction and that can attack the boron-nitride or carbon nanotubes. In the meantime, their quick solution to the problem is perhaps the simplest.
"Now we use glass-coated stir bars," Martí said. "Glass is completely inert. That gives us reproducibility and good functionalization."
###
David Ruth 713-348-6327 david@rice.edu
Mike Williams 713-348-6728 mikewilliams@rice.edu
Rice graduate student Carlos de los Reyes is lead author of the paper. Co-authors are Rice graduate student Ashleigh Smith McWilliams, research assistant Kendahl Walz-Mitra, undergraduate students Katharyn Hernandez and Selin Ergülin, and Matteo Pasquali, the A.J. Hartsook Professor of Chemical and Biomolecular Engineering and a professor of materials science and nanoengineering and of chemistry. Martí is an associate professor of chemistry, of bioengineering and of materials science and nanoengineering.
The National Science Foundation, the Air Force Office of Scientific Research and the Welch Foundation supported the research.
Read the abstract at https://pubs.acs.org/doi/10.1021/acsomega.8b03677
This news release can be found online at https://news.rice.edu/2019/03/29/odd-reaction-creates-a-stir-in-the-lab/
Follow Rice News and Media Relations via Twitter @RiceUNews.
Related materials:
New nano building block takes a bow: http://news.rice.edu/2018/05/21/new-nano-building-block-takes-a-bow/
Martí Research Group: http://martigroup.rice.edu
Department of Chemistry: http://chemistry.rice.edu
Wiess School of Natural Sciences: https://naturalsciences.rice.edu
Video:
Video produced by Brandon Martin/Rice University
Images for download:
https://news-network.rice.edu/news/files/2019/03/0401_STIR-1-WEB-2e2w2h6.jpg
Rice University chemists discovered that stir bars covered in PTFE, also known as Teflon, react with chemicals in an unexpected way during the modification of nanotubes through Billups-Birch reduction. The bars that start out (and usually stay) white turn black in the solution and alter the results. (Credit: Photo by Brandon Martin/Rice University)
https://news-network.rice.edu/news/files/2019/03/0401_STIR-2-WEB-2fwbps8.jpg
A pristine stir bar made of ferromagnetic metal with a PTFE, or Teflon, coating. Rice University chemists discovered the inert bars, which are commonly used to mix chemicals, cause unwanted results during Billups-Birch reactions with carbon and other nanotubes. (Credit: Photo by Brandon Martin/Rice University)
https://news-network.rice.edu/news/files/2019/03/0401_STIR-3-WEB-2mbo2ry.jpg
Rice University chemists who discovered that chemicals used in Billups-Birch reductions of carbon nanotubes react with the white PTFE stir bars, turning them black. They recommend using glass stir bars, like the one in the middle, for such reductions. (Credit: Photo by Brandon Martin/Rice University)
Located on a 300-acre forested campus in Houston, Rice University is consistently ranked among the nation's top 20 universities by U.S. News & World Report. Rice has highly respected schools of Architecture, Business, Continuing Studies, Engineering, Humanities, Music, Natural Sciences and Social Sciences and is home to the Baker Institute for Public Policy. With 3,962 undergraduates and 3,027 graduate students, Rice's undergraduate student-to-faculty ratio is just under 6-to-1. Its residential college system builds close-knit communities and lifelong friendships, just one reason why Rice is ranked No. 1 for lots of race/class interaction and No. 2 for quality of life by the Princeton Review. Rice is also rated as a best value among private universities by Kiplinger's Personal Finance.
Journal
ACS Omega