This release is available in French.
Montreal, June 9, 2009 – Antibiotics, antimicrobials and antifungals are seeping into the waterways of North America, Europe and East Asia, according to an investigation published in the peer-reviewed journal Environmental Health Perspectives (EHP). Authored by Université de Montréal and Environment Canada researchers, the review found that consumption of anti-infectives for human and agriculture use contributes to their release into the environment and even into drinking water.
"Anti-infectives are constantly discharged, at trace levels, in natural waters near urban centres and agricultural areas," says senior author Sébastien Sauvé, a Université de Montréal professor of environmental analytical chemistry. "Their potential contribution to the spread of anti-infective resistance in bacteria and other effects on aquatic biota is a cause for concern."
The research team compiled published data for three classes of antibiotics (macrolides, quinolones and sulfonamides) and the compound trimethoprim present in the urban wastewaters of East Asia, Europe and North America. The scientists found higher concentrations of these pharmaceuticals in raw wastewater compared to treated wastewater.
"Rivers, creeks, lakes, estuar¬ies, basins, sea waters and wells have been reported to be contaminated by several of these compounds," says Dr. Sauvé, adding that a previous review by the scientific team also demonstrated that pharmaceuticals could promote microbial resistance when released in the environment.
This latest review warns the increased farm usage of anti-infectives may augment their levels in future agricultural wastewater. The investigation also predicts that vital urban water conservation strategies could produce harmful side-effects -- specifically less wastewater resulting in lower dilution and higher concentrations of anti-infectives in wastewater.
"Anti-infectives might have a greater impact in developing countries, where sewage infrastructure can be lacking, over-the-counter drugs more widely available and industrial emissions less strict," adds first author Pedro A. Segura, a Université de Montréal PhD student.
About the study: "Review of the Occurrence of Anti-infectives in Contaminated Wastewaters and Natural and Drinking Waters," published in Environmental Health Perspectives, was authored by Pedro A. Segura, Matthieu François and Sébastien Sauvé of the Université de Montréal and Christian Gagnon of Environment Canada's Aquatic Ecosystem Protection Research Division.
Partners in research: This study was funded by the Fonds de Recherche sur la Nature et les Technologies du Québec, the St. Lawrence Action Plan, the Natural Sciences and Engineering Research Council of Canada and the Canadian Foundation for Innovation.
On the Web:
About the cited article in Environmental Health Perspectives www.ehponline.org/docs/2009/11776/abstract.html
About the Université de Montréal: www.umontreal.ca/english/index.htm
About the Department of Chemistry: www.chimie.umontreal.ca
About Sébastien Sauvé: www.mapageweb.umontreal.ca/sauves/main_eng.htm
Environmental Health Perspectives