February 17, 2016 -- Adults who use marijuana are five times more likely to develop an alcohol use disorder (AUD) --alcohol abuse or dependence-- compared with adults who do not use the drug. And adults who already have an alcohol use disorder and use marijuana are more likely to see the problem persist. Results of a study by researchers at Columbia University's Mailman School of Public Health and the City University of New York appear online in the journal Drug and Alcohol Dependence.
"Our results suggest that cannabis use appears to be associated with an increased vulnerability to developing an alcohol use disorder, even among those without any history of this," said Renee Goodwin, PhD, associate professor of Epidemiology at the Mailman School of Public Health. "Marijuana use also appears to increase the likelihood that an existing alcohol use disorder will continue over time."
The researchers analyzed data from 27,461 adults enrolled in the National Epidemiologic Survey on Alcohol and Related Conditions who first used marijuana at a time when they had no lifetime history of alcohol use disorders. The population was assessed at two time points. Adults who had used marijuana at the first assessment and again over the following three years (23 percent) were five times more likely to develop an alcohol use problem, compared with those who had not used marijuana (5 percent). Adult problem drinkers who did not use cannabis were significantly more likely to be in recovery from alcohol use disorders three years later.
"From a public health standpoint we recommend that further research be conducted to understand the pathways underlying these relationships as well as the degree to which various potentially vulnerable population subgroups -- youth, for example -- are at increased risk," noted Goodwin. "If future research confirms these findings, investigating whether preventing or delaying first use of marijuana might reduce the risk of developing alcohol use disorders among some segments of the population may be worthwhile."
Co-authors are Andrea Weinberger, Yeshiva University and Yale University School of Medicine; and Jonathan Platt, Mailman School of Public Health.
The study was supported by the National Institutes of Health/National Institute on Drug Abuse (grant R01-DA20892). The authors report no conflicts of interest.
About Columbia University's Mailman School of Public Health
Founded in 1922, Columbia University's Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Mailman School is the third largest recipient of NIH grants among schools of public health. Its over 450 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change & health, and public health preparedness. It is a leader in public health education with over 1,300 graduate students from more than 40 nations pursuing a variety of master's and doctoral degree programs. The Mailman School is also home to numerous world-renowned research centers including ICAP (formerly the International Center for AIDS Care and Treatment Programs) and the Center for Infection and Immunity. For more information, please visit http://www.mailman.columbia.edu
Drug and Alcohol Dependence