News Release

抗生素耐药性与DNA重组

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

Electron Micrograph of Two Contacting <I>E. coli</I> Bacteria.

image: Electron micrograph of two contacting E. coli bacteria. view more 

Credit: Image courtesy of Evgeni V. Sokurenko.

一项关于导致对一类常用抗生素氟奎诺酮类药物耐药的大肠埃希氏菌突变的研究发现,造成耐药性的3个单独的突变并不是通过一步步的进化获得的,而是通过在一种高耐药性和一种高致病性大肠埃希氏菌菌株之间的11个同时的基因重组而一次性获得的;这组作者说,其结果是一种大流行耐多药菌株的全球传播,该菌株很可能出现在过去12年内。

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