A new study from the University of Bristol supports body mass index (BMI) as a useful tool for assessing obesity and health.
A simple measure based on weight and height, BMI is widely used to assess if a person is of a healthy weight. But its reliability as a health measure is often criticized, as it does not distinguish fat from muscle and does not tell us where body fat is stored.
Using body scans from 2,840 young people aged 10 and 18 in Bristol's Children of the 90s population study, researchers examined BMI findings against more detailed measures of fat.
They studied the effects of total fat, along with fat in the trunk, arms and legs, on 230 different traits relevant to metabolism and future heart disease risk, such as cholesterol and blood pressure. These effects were compared with those seen when using BMI as a measure.
The study, published in the Journal of the American College of Cardiology, found that higher total fat at age 10 and 18 was associated with damaging levels of cardiometabolic traits such as higher blood pressure and adverse cholesterol and inflammatory profiles at age 18.
Effects appeared to worsen with time and were driven most by fat stored and gained in the trunk, although gains in leg fat also appeared harmful. Carrying more lean mass (assessed here as anything in the body that that isn't fat or bone) had less of an impact on traits and did not appear to protect against carrying more fat. Higher BMI showed similar effects as higher total and trunk fat, reflecting close overlap between these measures.
Dr Joshua Bell, an epidemiologist at the University of Bristol who led the study, commented: "BMI is often criticized. Our study asked how useful it really is for detecting the health effects of obesity by pitching it against more objective body scan measures. We found that trunk fat is the most damaging to health, but that simple BMI gives very similar answers to more detailed measures. This is good news since BMI is widely measured and costs virtually nothing."
"We're now in a better position to understand obesity in the young thanks to participants of the Bristol-based Children of the 90s study - they, and all study participants, make new insights possible."
"We now need to look at more detailed lean measures to see if other aspects protect against higher fat, and how this might differ between the sexes. This is more important than ever given stubbornly high rates of obesity worldwide."
Notes for editors
1. Associations of body mass and fat indexes with cardiometabolic traits by Joshua Bell, David Carslake, Linda O'Keefe, Monika Frysz, Laura Howe, Mark Hamer, Kaitlin Wade, Nicholas Timpson and George Davey Smith in Journal of the American College of Cardiology.
2. This study was funded by Cancer Research UK (Population Research), the Medical Research Council, Wellcome Trust, University of Bristol, and the National Institute for Health Research.
3. Based at the University of Bristol, Children of the 90s, also known as the Avon Longitudinal Study of Parents and Children (ALSPAC), is a long-term health-research project that enrolled more than 14,000 pregnant women in 1991 and 1992. It has been following the health and development of the parents and their index children in detail ever since and is currently recruiting the children of those original children into the study. It receives core funding from the Medical Research Council, the Wellcome Trust and the University of Bristol. Find out more at http://www.childrenofthe90s.ac.uk.
4. About Cancer Research UK
- Cancer Research UK is the world's leading cancer charity dedicated to saving lives through research.
- Cancer Research UK's pioneering work into the prevention, diagnosis and treatment of cancer has helped save millions of lives.
- Cancer Research UK receives no funding from the UK government for its life-saving research. Every step it makes towards beating cancer relies on vital donations from the public.
- Cancer Research UK has been at the heart of the progress that has already seen survival in the UK double in the last 40 years.
- Today, 2 in 4 people survive their cancer for at least 10 years. Cancer Research UK's ambition is to accelerate progress so that by 2034, 3 in 4 people will survive their cancer for at least 10 years.
- Cancer Research UK supports research into all aspects of cancer through the work of over 4,000 scientists, doctors and nurses.
- Together with its partners and supporters, Cancer Research UK's vision is to bring forward the day when all cancers are cured.
For further information about Cancer Research UK's work or to find out how to support the charity, please call 0300 123 1022 or visit http://www.cancerresearchuk.org. Follow us on Twitter and Facebook.
Journal of the American College of Cardiology