New research led by investigators from Boston Medical Center and Grady Memorial Hospital demonstrates the significant decline in hospitalizations for neurological emergencies during the COVID-19 pandemic. The rate of Subarachnoid hemorrhage (SAH) - bleeding in the space between the brain and the tissue covering the brain - hospitalizations declined 22.5 percent during the study period, which is consistent with the other reported decreases in emergencies such as stroke or heart attacks.
Published in Stroke & Vascular Neurology, the study compares subarachnoid hemorrhage hospital admissions for the months following throughout the initial COVID surge, in hospitals that bore a greater burdened by COVID-19, and those that did not.
"SAH is a global health burden, with high fatality and permanent disability rates, representing a potential impact of these emergent situations," said lead co-author Thanh N Nguyen, MD, FRCPc, a vascular and interventional neurologist at Boston Medical Center, and a professor of neurology and radiology at Boston University School of Medicine. "These neurological conditions can be life-threatening if care is not being promptly sought."
Other important data from this study includes the rate of embolization of ruptured aneurysms and aneurysmal SAH hospitalizations, which declined by 11.5 percent and 24.6 respectively.
Hospitals with a higher COVID-19 hospitalization burden were found to be more vulnerable to the decline in SAH admissions and ruptured aneurysm coiling volume. However, even hospitals with lower COVID-19 hospitalization burden were found to have decreases in SAH admissions, suggesting that access to hospital care was not the main factor for these decreases.
The cross-sectional, retrospective, observational study was done including data from six continents, 37 countries, and 140 comprehensive stroke centers. Patients with the diagnosis of SAH, aneurysmal SAH, ruptured aneurysm in need of coiling interventions, and COVID-19 were identified through prospective aneurysm databases and ICD-10 codes. Monthly and weekly admission volume data were collected over three periods of time: March 1, 2020, to May 31, 2020 (pandemic months), November 1, 2019, to February 29, 2020 (immediately preceding pandemic months), and March 1, 2019, to May 31, 2019 (equivalent period one year prior to pandemic). The findings are similar to reported decreases in SAH city-wide in Paris during a two-week period of the pandemic, and decreases in a Toronto hospital, whereas other cities such as Berlin and Joinville (South Brazil) reported no decreases in SAH during the COVID-19 pandemic.
High and intermediate procedural volume centers were more affected by declines in SAH hospitalizations and ruptured aneurysm embolization than low volume SAH coiling centers during the pandemic. However, hospitals with low SAH coiling volumes demonstrated an increase in the coiling of ruptured aneurysms during the pandemic, despite a significant decrease in total SAH admissions.
"This suggests a shift towards treating more patients with ruptured aneurysms with endovascular techniques during the pandemic to potentially shorten hospitalization times and mitigate risks of perioperative infection to the patient or provider," says Raul Nogueira, MD, director of neuroendovascular service at the Marcus Stroke & Neuroscience Center - Grady Memorial Hospital, lead co-investigator and professor of neurology and radiology at Emory University School of Medicine.
About Boston Medical Center
Boston Medical Center (BMC) is a private, not-for-profit, 514-bed, academic medical center that is the primary teaching affiliate of Boston University School of Medicine. It is the largest and busiest provider of trauma and emergency services in New England. BMC offers specialized care for complex health problems and is a leading research institution, receiving more than $166 million in sponsored research funding in fiscal year 2019. It is the 13th largest funding recipient in the U.S. from the National Institutes of Health among independent hospitals. In 1997, BMC founded Boston Medical Center Health Plan, Inc., now one of the top ranked Medicaid MCOs in the country, as a non-profit managed care organization. Boston Medical Center and Boston University School of Medicine are partners in Boston HealthNet - 12 community health centers focused on providing exceptional health care to residents of Boston. For more information, please visit http://www.bmc.org.
About Grady Health System
Grady Health System is one of the largest safety net health systems in the nation and includes the 953-bed Grady Memorial Hospital, five neighborhood health centers, the Ponce de Leon HIV/AIDS Center, and Crestview Health & Rehabilitation Center. With nationally acclaimed emergency medical services, Grady has Atlanta's premier Level 1 trauma center - Metro Atlanta's only nationally verified Level 1 center - and serves as the 911 ambulance provider for the city of Atlanta. Grady's American Burn Association/American College of Surgeons verified Burn Center is one of only two in the state. And the Marcus Stroke and Neuroscience Center is a Joint Commission designated Advanced Comprehensive Stroke Center.
Stroke and Vascular Neurology