News Release

Noninvasive ventilation during exercise training beneficial in patients with COPD

Peer-Reviewed Publication

American College of Chest Physicians

MONTRÉAL (October 19, 2015)-- Researchers from Turkey's Ege University Department of Biostatistics evaluated the effects of noninvasive ventilation (NIV) and supplemental oxygen during exercise training (ET) and found it to have multiple physiologic benefits in patients with severe COPD. Results showed that supplemental oxygen during exercise helped to reduce hyperinflation and improve respiratory muscle function and exercise capacity.

The study consisted of 35 patients with COPD who underwent training for 8 weeks. Each group was randomized to either ET+NIV+O2, ET+O2, or ET alone. While no significant changes were found in ET alone, improvement in depression and walking distance increased in both of the other groups. Results from this study found a decrease in total lung capacity in patients who received ET+NIV+O2 but no significant change in ET+O2 patients.

"The study concluded that adding noninvasive ventilation to oxygen during exercise training in patients with severe COPD was a useful adjunct for improving breathlessness. It reduced hyperinflation and rates of depression, while improving respiratory muscle strength and quality of life measures," said Mark J. Rosen, MD, Master FCCP, CHEST Medical Director.


Further results will be shared during CHEST 2015 on Monday, October 26, at 7:30 AM at Palais des Congrès de Montréal, room 513ef. The study abstract can be viewed on the CHEST website.

CHEST Annual Meeting 2015 is the 81st annual meeting of the American College of Chest Physicians, held October 24-28, 2015, in Montréal, Canada. The American College of Chest Physicians, publisher of the journal CHEST, is the global leader in advancing best patient outcomes through innovative chest medicine education, clinical research, and team-based care. Its mission is to champion the prevention, diagnosis, and treatment of chest diseases through education, communication, and research. It serves as an essential connection to clinical knowledge and resources for its 18,700 members from around the world who provide patient care in pulmonary, critical care, and sleep medicine. For more information about CHEST 2015, visit, or follow the CHEST meeting hashtag, #CHEST2015, on social media.

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