News Release

驯化与大脑形态

Peer-Reviewed Publication

Proceedings of the National Academy of Sciences

Illustration of Differences in the Amygdala and the Medial Prefrontal Cortex Between Domestic

image: Illustration of differences in the amygdala (orange) and the medial prefrontal cortex (blue) between domestic (right) and wild rabbits (left). view more 

Credit: Image courtesy of Fabian Sinzinger (KTH Royal Institute of Technology, Stockholm).

一项研究探索了与兔的驯化有关的遗传变化与大脑结构。家养动物与他们的野生祖先有差异,以至于与人类密切接出也不会引发争斗反应或进攻性的行为。此前对野兔和家兔的研究已经发现了涉及大脑或神经发育的基因的变化对于驯化具有重要性。为了研究这类遗传变化的表现型效应,Leif Andersson 及其同事使用高分辨率磁共振成像(MRI)分析了野兔与家兔大脑的灰质体积与白质微结构。与野兔相比,家兔的大脑的杏仁核更小,内侧前额叶皮层更大。家兔体积减少的区域涉及了恐惧探测、学习和表达,而体积增加的区域涉及了调控消极情绪。这组作者还发现,白质神经束各向异性广泛减少,这与神经速度减少以及信息处理的折中相一致。这组作者说,这些结果提示,与驯化有关的遗传变化可能导致大脑结构的减少恐惧的变化。

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