The research team of the Department of Organic Chemistry of Samara Polytech under the leadership of Doctor of Chemical Sciences, Head of the Department Yuri Klimochkin and Doctor of Chemical Sciences, Professor Alexander Reznikov in cooperation with the crystallographic research group of Lomonosov Moscow State University (supervisor - candidate of chemical sciences, senior researcher Victor Rybakov) completed a study to obtain non-racemic 4,5-dihydrofurans based on Michael addition and study their chemical properties. The announcement of a scientific article with the results of the latest research is posted on the cover of the authoritative journal Tetrahedron.
"Studying the method of obtaining non-racemic 4,5-dihydrofurans will make it possible to create biologically active compounds, and it is also possible that some of them are potential drugs against cancer, neurodegenerative diseases," Dmitry Nikerov, assistant of the Department of Organic Chemistry says.
An important advantage of the scientific developments of the team is the widespread use of cheap complexes of base metals such as nickel.
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Scientists are investigating ways to obtain non-racemic heterocycles based on the methods of asymmetric metal complex catalysis with the financial support of the Russian Science Foundation (grant 18-13-00447).
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Samara Polytech as a flagship university offers a wide range of education and research programs and aims at development and transfer of high-quality and practically-oriented knowledge. The university has an established reputation in technical developments and focuses on quality education, scientific and pragmatic research, combining theory and practice in the leading regional businesses and enterprises. Education is conducted in 30 integrated groups of specialties and areas of training (about 200 degree programs including bachelor, master programs and 55 PhD programs) such as oil and gas, chemistry and petrochemistry, mechanics and energy, transportation, food production, defense, IT, mechanical and automotive engineering, engineering systems administration and automation, material science and metallurgy, biotechnology, industrial ecology, architecture, civil engineering and design, etc.
The international research journal Tetrahedron is known all over the world for its rich history, as well as for the works of great chemists, whose contribution to the development of science is of great value. The journal is published by Elsevier in the Netherlands and is indexed in the Scopus and Web of Science databases. Tetrahedron publishes research of great importance in organic chemistry and related disciplines such as organic materials and bioorganic chemistry.
Journal
Tetrahedron