Multimedia Release 5-Aug-2021

Using two CRISPR enzymes, a COVID diagnostic in only 20 minutes

Eliminating initial RNA amplification simplifies and speeds up assay for SARS-CoV-2 virus

Peer-Reviewed Publication

University of California - Berkeley

image: The reactions involved in the FIND-IT assay to detect infection with the SARS-CoV-2 virus. When the Cas13 enzyme (bottom left) binds to its target RNA, it snips a molecule (orange and light blue ribbon) to release an activator (orange) that supercharges the Csm6 nuclease (right) to cleave and release fluorescent molecules that light up (green) and signal the presence of viral RNA. view more

Credit: Artwork courtesy of Margaret L. Liu, University of Chicago Pritzker School of Medicine

Journal

Nature Chemical Biology

DOI

10.1038/s41589-021-00842-2

Method of Research

Experimental study

Subject of Research

Human tissue samples

Article Title

Accelerated RNA detection using tandem CRISPR nucleases

Article Publication Date

5-Aug-2021

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