Multimedia Release

Using two CRISPR enzymes, a COVID diagnostic in only 20 minutes

Eliminating initial RNA amplification simplifies and speeds up assay for SARS-CoV-2 virus

Peer-Reviewed Publication

University of California - Berkeley

FIND-IT assay

image: The reactions involved in the FIND-IT assay to detect infection with the SARS-CoV-2 virus. When the Cas13 enzyme (bottom left) binds to its target RNA, it snips a molecule (orange and light blue ribbon) to release an activator (orange) that supercharges the Csm6 nuclease (right) to cleave and release fluorescent molecules that light up (green) and signal the presence of viral RNA. view more 

Credit: Artwork courtesy of Margaret L. Liu, University of Chicago Pritzker School of Medicine

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