Acute kidney injury in deceased donor kidney associated with graft survival

Study published in the American Journal of Kidney Diseases (AJKD) shows ongoing acute kidney injury (AKI) or AKI in recovery in a deceased donor kidney is associated with lower graft survival

Although deceased-donor acute kidney injury (AKI) portends an increased risk of delayed graft function in the short term, its impact on long-term graft survival is a matter of ongoing debate. Most of the existing studies did not show any association between donor AKI and graft survival. By refining donor AKI classification in accordance with international guidelines, researchers found that not only ongoing donor AKI but also the presence of at least one abnormal serum creatinine value during procurement were associated with lower graft survival in kidney transplant recipients.

ARTICLE TITLE: Association Between Deceased Donor Acute Kidney Injury Assessed Using Baseline Serum Creatinine Back-Estimation and Graft Survival: Results From the French National CRISTAL Registry

AUTHORS: Rémi Lenain, MD, Camille Prouteau, MD, Aghilès Hamroun, MD, Yohann Foucher, PhD, Magali Giral, PhD, Mehdi Maanaoui, MD, and Marc Hazzan, PhD, on behalf of the Contributors to the CRISTAL National Registry

DOI: https://doi.org/10.1053/j.ajkd.2021.06.022