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AI can calculate personalized risk of having another stroke, new study shows

Artificial intelligence (AI) can be used to give stroke patients a personalized and more accurate risk for suffering a recurrence, according to a new study presented today at the European Stroke Organization (ESO) Conference

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Artificial intelligence (AI) can be used to give stroke patients a personalised and more accurate risk for suffering a recurrence, according to a new study presented today at the European Stroke Organisation (ESO) Conference1.

Experts believe the study will help to identify the most important factors for preventing stroke recurrence and has the potential to help prevent many thousands of strokes a year in Europe, and in doing so prevent many deaths and cases of disability.

According to previous research, one in four stroke survivors will have another stroke2 and yet up to 80 per cent might be prevented with the right treatments and lifestyle changes3. The number of people living with stroke is estimated to rise by 27% between 2017 and 2047 in the European Union, mainly due to an increase in the number of people over 704.

The study used calculations based on both non-modifiable risk factors, such as age and ethnicity, and modifiable lifestyle risk factors and habits such as smoking, weight, blood pressure and cholesterol, diet, obesity, physical activity levels and treatment compliance, as well as socio-economic factors. These can be used to make a more accurate prediction of an individual’s risk of having a stroke recurrence, within 3 months, one year, and more than a year, helping to prevent a recurrence and improve patient’s treatment adherence.

The research, conducted by scientists from Vall d’ Hebrón University, Barcelona, Spain, used a dataset of 41,325 patients admitted with a stroke diagnosis in 88 public hospitals over six years, and fed them into an AI-based model which was able to provide an individualised risk of stroke recurrence at three and 12 months.

Lead author Giorgio Colangelo, AI Research Manager at Vall d’ Hebrón University Hospital’s Institute of Research (VHIR), Barcelona, Spain, commented, “We were able to use AI to predict the stroke recurrence at 3 and 12 months on an individual level, and knowing this risk has clinical value for doctors and for patients. Risk factors included high blood pressure and raised cholesterol, atrial fibrillation or sleep apnoea. We also determined and quantified what are the most relevant risk factors and which of them each patient can modify in his or her lifestyle.”

Dr. Marta Rubiera, Neurologist at Vall d’ Hebrón University Hospital and coordinator of the study, added, “We hope the data may be used to create a much more personalised prediction of if, and when, patients might have another stroke, and that by explaining the impact of individual risk factors, it will make patients more likely to comply with any treatment prescribed or lifestyle changes suggested, reducing the likelihood of having another stroke”.

Dr. Marc Ribo, Interventional Neurologist, and Chief Scientific Officer at Nora Health, which also participated in the study, concluded “Patient awareness and empowering self-care are crucial to reduce the risks of recurrent stroke. This study will help inform the personalisation of a recently developed app, NORA and greatly improve patients’ risk management.”

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Notes to Editors:

A reference to the European Stroke Organisation (ESO) Conference must be included in any coverage or articles associated with this study and research.

For more information or to arrange an expert interview, please contact Luke Paskins or Sean Deans on luke.paskins@emotiveagency.com, sean.deans@emotiveagency.com or press@eso-stroke.org, or call +44 (0) 208 154 6396.

About the Study Authors:

Giorgio Colangelo, PHD, is AI Research Manager at Vall d’ Hebrón University Hospital’s Institute of Research (VHIR), Barcelona, Spain.

Dr. Marta Rubiera is a Neurologist at Vall d’ Hebrón University Hospital, Barcelona, Spain.

Dr. Marc Ribo is a Interventional Neurologist and Chief Scientific Officer at Nora Health.

About ESO:

The European Stroke Organisation (ESO) is a pan-European society of stroke researchers and physicians, national and regional stroke societies, and lay organisations, founded in December 2007. The ESO is an NGO comprised of individual and organisational members. The aim of the ESO is to reduce the burden of stroke by changing the way that stroke is viewed and treated. This can only be achieved by professional and public education and making institutional changes. ESO serves as the voice of stroke in Europe, harmonising stroke management across the whole of Europe and taking action to reduce the burden.

Four Facts on Stroke:

  1. In 2017, there were 1.12 million first strokes in the EU, 9.53 prevalent stroke cases and 460,000 stroke-related deaths4
  2. In 2017, there were 7.06 million disability adjusted years lost due to stroke in the EU4
  3. By 2047 it has been estimated there will be an additional 40,000 strokes per year in the EU (a rise of 3%)4
  4. 80% of premature heart disease and stroke is preventable5

References:

  1. A personalised recurrence stroke predictor based on artificial intelligence, presented at the European Stroke Organisation Conference, 1 September 2021
  2. https://www.stroke.org/en/life-after-stroke/preventing-another-stroke
  3. https://actionplan.eso-stroke.org/domains/secondary-prevention/
  4. https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.029606
  5. https://www.euro.who.int/en/health-topics/noncommunicable-diseases/cardiovascular-diseases/data-and-statistics

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