Bottom Line: The U.S. Preventive Services Task Force (USPSTF) recommends the use of low-dose aspirin (81mg/d) as preventive medication for preeclampsia after 12 weeks of gestation in individuals who are at high risk for preeclampsia. A multisystem inflammatory syndrome that is often progressive, preeclampsia is one of the most serious health problems that affect pregnant individuals. It is a complication in approximately 4 percent of pregnancies in the United States. The USPSTF routinely makes recommendations about the effectiveness of preventive care services and this statement updates and is consistent with its 2014 recommendation and is strengthened by new evidence from additional trials demonstrating reduced risks of perinatal death with low-dose aspirin use.
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